We establish fractional integral and derivative formulas by using Marichev-Saigo-Maeda operators involving the S-function. The results are expressed in terms of the generalized Gauss hypergeometric functions. Corresponding assertions in terms of Saigo, Erdélyi-Kober, Riemann-Liouville, and Weyl type of fractional integrals and derivatives are presented. Also we develop their composition formula by applying the Beta and Laplace transforms. Further, we point out also their relevance.Hindawi Abstract and Applied Analysis Volume 2019, Article ID 6487687, 19 pages https://doi.org/10.1155/2019/6487687 . . . − / ] ] ] ] . (116) Proof. The proof of Theorem 38 is a similar manner of Theorem 37. Theorem 39. Let , , V, V , , , , , , ∈ C, ∈ R, , ∈ N, R( ) > R( ), > 0, and Abstract and Applied Analysis 15 < + 1, where ( = 1, . . . , ), such that R( ) > 0, R( ) > max{0, R( − − − V ), R(V − )}, then the following fractional derivative formula holds true: ((