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Aims Central adiposity is associated with increased cardiovascular disease (CVD) risk, even among people with normal body mass index (BMI). We tested the hypothesis that regional body fat deposits (trunk or leg fat) are associated with altered risk of CVD among postmenopausal women with normal BMI. Methods and results We included 2683 postmenopausal women with normal BMI (18.5 to <25 kg/m2) who participated in the Women’s Health Initiative and had no known CVD at baseline. Body composition was determined by dual energy X-ray absorptiometry. Incident CVD events including coronary heart disease and stroke were ascertained through February 2017. During a median 17.9 years of follow-up, 291 incident CVD cases occurred. After adjustment for demographic, lifestyle, and clinical risk factors, neither whole-body fat mass nor fat percentage was associated with CVD risk. Higher percent trunk fat was associated with increased risk of CVD [highest vs. lowest quartile hazard ratio (HR) = 1.91, 95% confidence interval (CI) 1.33–2.74; P-trend <0.001], whereas higher percent leg fat was associated with decreased risk of CVD (highest vs. lowest quartile HR = 0.62, 95% CI 0.43–0.89; P-trend = 0.008). The association for trunk fat was attenuated yet remained significant after further adjustment for waist circumference or waist-to-hip ratio. Higher percent trunk fat combined with lower percent leg fat was associated with particularly high risk of CVD (HR comparing extreme groups = 3.33, 95% CI 1.46–7.62). Conclusion Among postmenopausal women with normal BMI, both elevated trunk fat and reduced leg fat are associated with increased risk of CVD.

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The purpose of the present study, grounded in self-determination theory, was to explore the relationship between Paralympic athletes' perceptions of autonomy-supportive coach behavior basic psychological needs, and intrinsic motivation to know, accomplish, and experience stimulation. One hundred thirteen Canadian Paralympic athletes completed an online survey, consisting of measures of coach autonomy support; of perceptions of autonomy, competence, and relatedness; and of intrinsic motivation. Perceived coach autonomy support was a predictor of athletes' perceptions of autonomy and relatedness. Perceived competence was a significant predictor of all three forms of intrinsic motivation, while perceived autonomy was a significant predictor of intrinsic motivation to accomplish and experience stimulation. The results highlight the important relationship between coach behavior and athlete motivation in disability sport.