Objective: To compare the obstetric and neonatal outcomes of pregnant women in the adolescent age group with the outcomes of those in reproductive age group in our region. Materials and Methods: The outcomes of 539 adolescent pregnancies between the ages of 10-19 years and 644 adult pregnancies between the ages of 20-35 years who gave birth in Osmaniye State Hospital Obstetrics and Gynecology Clinic between January 2013 and January 2015 were analyzed retrospectively. Results: The mean age of the adolescent group was determined as 17.60 ± 1.21, and the mean age of the adult group was detected as 26.77 ± 3.94. Compared to reproductive age group, in adolescent age group gestational diabetes mellitus (4.5%, 9.2%, respectively) and preterm birth (32.5%, 19.9%) incidence was detected to be significantly high (p<0.05). 1-minute and 5-minute APGAR scores were observed significantly low in adolescent age group. Conclusion: It is observed that adverse maternal and perinatal results are increased in pregnant women in adolescent age group compared to reproductive age group.
Objective: The aim of the study assess efficacy of hematological biomarkers for predicting the stage of endometriosis.
Materials and methods: Patients underwent surgery and diagnosed with endometriosis confirmed by pathology report between January 2015-December 2020 were included. Individuals were divided into two groups as stage 1-2-3 and stage 4 patients.
Results: 91 patients with stage 1-2-3 and 105 with stage 4 endometriosis were identified. There was no significant relationship between endometriosis score and complete blood count parameters. However, endometriosis score revealed a significant correlation with serum CA125 level and the combined markers including CA125. The logarithm of the CA 125 was used to predict the endometriosis score. In order to quantify the relationship, a univariate linear model was performed to predict the endometriosis score with log (CA 125). It demonstrated for every increase in the level of log (CA 125), endometriosis score increased by 8.57 (β=8.57. R2=0.115. p<0.001). The p values of alternative parameters analyzed to predict the stage of endometriosis. p-values were 0.263 for neutrophile/lymphocyte; 0.457 for platelet/lymphocyte; 0.790 for red cell distribution width/lymphocyte and 0.842 for mean platelet volume/lymphocyte ratios.
Conclusion: CA 125 alone was found substaintally efficient in predicting endometriosis stage preoperatively.
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