Purpose: In recent years, there has been increased clinical interest in the right ventricle (RV) of the heart. RV dysfunction is an important prognostic marker for several cardiac diseases. Accurate modeling of the RV shape is important for estimating the performance. We have created computationally effective models that allow for accurate estimation of the RV shape.Approach: Previous approaches to cardiac shape modeling, including modeling the RV geometry, has used Doo-Sabin surfaces. Doo-Sabin surfaces allow effective computation and adapt to smooth, organic surfaces. However, they struggle with modeling sharp corners or ridges without many control nodes. We modified the Doo-Sabin surface to allow for sharpness using weighting of vertices and edges instead. This was done in two different ways. For validation, we compared the standard Doo-Sabin versus the sharp Doo-Sabin models in modeling the RV shape of 16 cardiac ultrasound images, against a ground truth manually drawn by a cardiologist. A Kalman filter fitted the models to the ultrasound images, and the difference between the volume of the model and the ground truth was measured. Results:The two modified Doo-Sabin models both outperformed the standard Doo-Sabin model in modeling the RV. On average, the regular Doo-Sabin had an 8-ml error in volume, whereas the sharp models had 7-and 6-ml error, respectively.Conclusions: Compared with the standard Doo-Sabin, the modified Doo-Sabin models can adapt to a larger variety of surfaces while still being compact models. They were more accurate on modeling the RV shape and could have uses elsewhere.

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Purpose: 3D transesophageal echocardiography (TEE) has become an important modality for pre-and peri-operative imaging of valvular heart disease. TEE can give excellent visualization of valve morphology in 3D rendering. As a convention, 3D TEE images are reformatted in three standard views. We describe a method for automatic calculation of parameters needed to define the standard views from 3D TEE images using no manual input.Approach: An algorithm was designed to find the center of the mitral valve and the left ventricular outflow tract (OT). These parameters defined the three-chamber view. The problem was modeled as a state estimation problem in which a 3D model was deformed based on shape priors and edge detection using a Kalman filter. This algorithm is capable of running in real time after initialization. Results:The algorithm was validated by comparing the automatic alignments of 106 TEE images against manually placed landmarks. The median error for determining the mitral valve center was 7.1 mm, and the median error for determining the left ventricular OT orientation was 13.5 deg. Conclusion:The algorithm is an accurate tool for automating the process of finding standard views for TEE images of the mitral valve.

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