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In the human urethra, phenylephrine-induced contractions were mediated through alpha1L-adrenoceptors and not through alpha1A-adrenoceptors. Contractions of the human urethra induced by NS-49 were also mediated mainly through alpha1L-adrenoceptors, with high potency and moderate efficacy. NS-49 may therefore be useful for the treatment of urinary stress incontinence, with minimal side-effects because it has subtype selectivity.

A single-chip H.264/MPEG-4 audiovisual LSI for mobile applications including terrestrial digital broadcasting systems such as ISDB-T and DVB-H with a module-wise dynamic voltage/frequency scaling architecture is fabricated in a 90nm 6M CMOS technology. This LSI operates even during the voltage/frequency transition, so there is no performance overhead. Voltage/frequency scaling is realized by a dynamic deskewing system and an on-chip voltage regulator with slew rate control. Figure 7.3.1 shows a micrograph of the chip equipped with four optimally configured RISC processors, dedicated hardware accelerators for specific signal processing, 32Mb embedded DRAM and interfaces for camera, display, audio and network streaming for mobile multimedia applications. The power consumed when decoding QVGA (320x240) H.264 baseline profile level 1.2 video streams at 15frames/s and MPEG-4 AAC LC is only 90mW. The chip features are summarized Fig. 7.3.2.H.264 and MPEG-4 standards play essential roles in the field of mobile multimedia. H.264 is a video compression standard adopted for terrestrial digital broadcasting. Demands for larger image size, higher frame rate and higher image quality are ever increasing. These demands require larger memory capacity and higher operating frequency, both resulting in higher power consumption, which is unacceptable for battery-powered mobile equipments. The LSI described in this paper decodes CIF (352x288) H.264 baseline profile at level 2, or encodes VGA (640x480) MPEG-4 SP @L4a video stream at 30 frames/s while encoding/decoding audio/speech streams and multiplexing/demultiplexing them at 180MHz. Figure 7.3.3 shows the block diagram of the chip.There are four major modules: video frontend, video backend, audio/speech and multiplexer/demultiplexer. Each of the modules consists of an optimally configured 32b media-embedded processor (MeP) core [1] and dedicated hardware accelerators for its specific operation. These modules, peripheral interface units for camera, display, mic/speaker, network, etc. and embedded DRAM are connected via a 64b main bus. As for voltage and frequency, this chip slows down the audio module independently from the rest of the chip. The audio module is decoupled by a voltage/frequency socket from the main bus and an on-chip voltage regulator and a dynamic deskewing system (DDS) for the dynamic voltage/frequency scaling.H.264, compared to previous video standards, requires very high programmability so it is very difficult to implement in dedicated hardware accelerators. By studying data processing procedures, elementary processes, are allocated to the processor core or the hardware accelerators, including a context adaptive variable length decoder. Cooperation between the processor core and dedicated hardware accelerators have successfully reduced a large amount of operation time and power consumption without losing the programmability necessary for H.264. Traditional power reducing techniques such as embedded DRAM, clock gating and gated I/O are implemented as in previous w...

weeks. Postoperative ultrasonography and IVU Case reportrevealed an almost normal left kidney. There was no recurrence of the left flank pain by the 36-month A 7-year-old boy presented with a history of dull pain in the left flank; IVU revealed a large hydronephrotic left follow-up. kidney with a filling defect in the upper ureter. There was no VUR and the diuretic renogram showed a left Comment ureteric obstruction and normal plasma flow in the left kidney. The preoperative diagnosis was left hydroneph-The congenital ureteric valve is relatively rare; only 30 cases have been reported to date (17 males and 13 rosis due to a ureteric polyp. A percutaneous endoscopic resection of the ureteric polyp was planned. Cystoscopy females, age range 10-94 years). Thirteen cases were associated with other congenital abnormalities [1][2][3]. revealed two normal ureteric orifices, and a retrograde pyelogram showed a filling defect of the upper ureter;The valve was on the left side in 16 cases, on the right in 13 and bilateral in one case. Eleven were located in the stenotic part of the ureter was tortuous (Fig. 1). A percutaneous nephrostomy dilated to 15 F was the upper ureter and the remainder in the lower ureter; 16 were annular, 13 were cusp-like and one was not placed through the upper calyx and the filling defect visualized using a multifunctional surgical endoscope described. Of 24 such patients who had undergone surgical treatment, nephrectomy or heminephrectomy (Universaltome, 13.5 F, Takai Co., Japan). The irregularities were not polyps but rather a ureteric valve of an was performed in nine, and 15 were treated with excision and end-to-end anastomosis. In the present case, the iris-like annular shape (Fig. 2). Using a hook-shaped cold knife, a 2 cm cut was made in the dorsal side of the ureteric stenosis was corrected by incision on the dorsal side of the ureter. Endoscopic incision is thought to be a valve until the yellowish peritoneal fat was visible. A 12 F indwelling endopyelotomy stent was used for useful treatment for the ureteric valve.