Background: Pain during the neonatal period has been associated with immediate and long-term adverse effects. One of the most frequent painful procedures that neonates face in neonatal intensive care unit is the endotracheal intubation. Midazolam has been a candidate for premedication before neonatal intubation. Our aim was to evaluate the effects of midazolam as the premedication on endotracheal intubation of premature infants during surfactant administration. Materials and Methods: In a double-blind clinical trial, 80 preterm infants were undertaken for tracheal intubation following the use of atropine associated to either midazolam or placebo. Patient's vital signs and general conditions were constantly monitored, and pain was assessed using premature infant pain profile (PIPP) score. Results: The mean ± standard deviation for postnatal age was 95.38 ± 50.04 and 111.63 ± 49.4 min in control and midazolam groups, respectively. The patients in the midazolam group had significantly better outcomes across several intubation outcome measures such as duration of endotracheal intubation (23.5 ± 6.7 vs. 18.8 ± 4.8 s, P = 0.001), oxygen saturation level (88.05% ±13.7 vs. 95.1 ± 1.8%, P = 0.002), intubation failure (34.2% vs. 2.5%, P = 0.0001), awake and resistance during intubation (95% vs. 20%, P = 0.0001), and excellent patient condition during intubation (0% vs. 82.5%, P = 0.0001). In addition, PIPP score was significantly lower in the midazolam group (5.2 ± 2.06 vs. 12.9 ± 2.9, P = 0.0001). Conclusion: Premedication with midazolam in newborns before intubation, can hold promising effects that manifests as better overall outcomes, less complications, better vital signs, more comfortable situation, and lesser pain for these patients.

The study was conducted to review, categorize and organize early tele-homecare follow-up research in premature infants based on research type, the focus of tele-homecare, and measured outcomes. This narrative review was conducted in 2021 through international databases, including PubMed, Scopus, ProQuest, and Web of Science databases. Studies selected for this purpose included original articles on premature infants. We reviewed 16 out of 267 identified articles. These studies were analyzed according to general characteristics, elements, and characteristics of tele-homecare intervention. Based on the obtained data, most studies had been conducted in Nordic countries as the pioneer in tele homecare. Also, most of them were on the psychological status of premature infants’ parents. Phone calls, video consultation, and applications were considered dominant tele-homecare communication tools. Overall, the qualitative studies on parents’ and health providers’ views about tele homecare revealed its hidden aspects as a supportive tool. The tele-homecare studies were distributed across different fields and countries, resulting in positive outcomes for infants and parents. However, further studies in the long-term periods are recommended to follow up on premature infants.

Background: The transition to telehealth services for mothers of preterm babies is a challenge in promoting the health of preterm infants, although telehealth allows real-time interaction and support for mothers. Aim: To compare the experiences of mothers of hospitalized and discharged preterm infants with telehealth services in the Islamic Republic of Iran. Methods: This qualitative study was conducted from June to October 2021 using a conventional content analysis approach. The study participants included 35 hospitalized and 35 discharged mothers of preterm infants, who received healthcare consultations through WhatsApp and Telegram applications. They were selected using purposive sampling. Data collection was done using in-depth semi-structured interviews and data analysis was performed using Graneheim and Lundman analysis. Results: Our findings showed request for continuing healthcare support by the mothers as the main category, with 3 subcategories: willingness to connect to telehealth services, more comprehensive education about telehealth services, and opportunities to share experiences. Mothers of hospitalized and discharged preterm infants had conflicting views about the ambiguous role of nurses in telehealth and the use of telehealth as a support system. Conclusion: Telehealth plays an important role as a supportive method in promoting infant health and boosting the confidence of mothers of preterm infants as they continuously interact with nurses.