There has been growing attention toward the predictive value of the coagulation parameters abnormalities in COVID-19. The aim of the study was to investigate the role of coagulation parameters namely Prothrombin concentration (PC), activated Partial thromboplastin Time (aPTT), D-Dimer (DD), Anti Thrombin III (ATIII) and fibrinogen (Fg) together with hematological, and biochemical parameters in predicting the severity of COVID-19 patients and estimating their relation to clinical outcomes in hospitalized and severe COVID-19 Patients. In a prospective study, a total of 267 newly diagnosed COVID-19 patients were enrolled. They were divided into two groups; hospitalized group which included 144 patients and non-hospitalized group that included 123 patients. According to severity, the patients were divided into severe group which included 71 patients and non-severe group that included 196 patients who were admitted to ward or not hospitalized. Clinical evaluation, measurement of coagulation parameters, biochemical indices, outcome and survival data were recorded. Hospitalized and severe patients were older and commonly presented with dyspnea (P ≤ 0.001). Differences in coagulation parameters were highly significant in hospitalized and severe groups in almost all parameters, same for inflammatory markers. D-dimer, AT-III and LDH showed excellent independently prediction of severity risk. With a cut-off of > 2.0 ng/L, the sensitivity and specificity of D dimer in predicting severity were 76% and 93%, respectively. Patients with coagulation abnormalities showed worse survival than those without (p = 0.002). Early assessment and dynamic monitoring of coagulation parameters may be a benchmark in the prediction of COVID-19 severity and death.

P300 latency delay may reflect some sort of cognitive impairment in patients with adenoid hypertrophy. This delay was reversible after adenoidectomy. Event-related potentials may help for assessment of cognitive functions in patients with adenoid hypertrophy.

Background:severe preeclampsia (PET) is one of the hypertensive diseases of pregnancy associated with significant morbidity and mortality and require special monitoring, lung ultrasonography is a novel monitoring and diagnostic tools in intensive care and widely used nowadays with early detection of pulmonary oedema. Patients and Methods:this was a cross sectional study of 55 patients with severe preeclampsia,35 case with eclampsia and 60 healthy controls. Lung ultrasonography was done to detect B lines in 12 lung zone postoperatively in both cases and controls fluid input and output is encounted. Results:Median (Min-Max) of lung sonar was higher in severe PET than in controls p value = .0001. B lines were observed in 47.2% and 8.3% in eclampsia ,severe PET and controls respectively. There was highly statistically significant difference between cases and controls as regards input and output as (P=.005), (P=.003) respectively as input and output was higher in control group than cases group) While there was no statistical significance difference between cases and controls as regards net balance as (P=.09). complications occur in higher percentage in cases than control. Conclusions: Restrictedfluid policy is indicated with the finding of B pattern especially with higher lung ultrasound score. Early management in patients with high B line score (pulmonary congestion) even before development of clinical manifestations should be considered.

Background: Severe preeclampsia (PE) and eclampsia are a hypertensive disease of pregnancy associated with significant morbidity and mortality and require special monitoring. Lung ultrasonography and transthoracic echocardiography are a novel monitoring and diagnostic tools in intensive care and are widely used nowadays. Objective: To detect the role and value of transthoracic echocardiography (TTE) in postoperative monitoring in patients with severe PE. Patients and Methods: This was a cross sectional study of 55 patients with severe preeclampsia, 35 patients with eclampsia and 60 healthy controls. Transthoracic echocardiography was done to evaluate diastolic function using E/A ratio with continuous wave Doppler, ejection fraction using M mode in long axis parasternal view and inferior vena cava (IVC) diameter in subcostal view. All measurements were done postoperatively. Results: There was significant difference between the 3 groups regarding diastolic function (p value 0.0001). Abnormal diastolic function in severe PE, eclampsia and controls was 81.2%, 94.3% and 5% respectively. There was no difference between the 3 groups of the study as regard IVC diameter. There was significant difference between the 3 groups as regards EF (P=0.007), the mean of EF in severe PE, eclampsia and controls was 66. 89 ± 5.54, 63.029 ± 8.45 and 66.43 ± 4.16 respectively. Conclusions: The use of transthoracic echocardiography is mandatory in postoperative monitoring in patients with severe PE and eclampsia as they can adjust management and detect complications. Restricted fluid therapy policy is indicated with the higher grades of diastolic dysfunction and lower ejection fraction (EF).