A Chinese woman in her 40s presented to the emergency department with a reduced level of consciousness. She had a 5-year history of depression with apathy, insomnia, and suicidal tendencies, which was refractory to paroxetine and buspirone. For a few weeks prior to admission, her husband had noticed prominently nocturnal dyspnea. One week before admission, she developed headache, fever, and vomiting, which persisted until hospitalization. Soon after admission, she had a generalized seizure, and within 24 hours, she underwent intubation for status epilepticus.During a 2-month stay in the intensive care unit with refractory seizures, there were 4 abnormal investigations that led to a
The data suggest that LRRK1 variant (rs2924835) and LRRK2 variants (rs34594498, rs34410987, and rs33949390) are not associated with ET in this Han Chinese population.
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