No abstract

To report the outcome of simultaneous bilateral nephrectomy (SBN) and living donor renal transplantation (LDRT) for Autosomal Dominant Polycystic Kidney Disease (ADPKD) in our center.Methods: retrospective comparative chart review study between ADPKD patients who underwent SBN and LDRT (group A) and ADPKD patient who underwent LDRT only (group B) at our center.Results: From May 2010 to August 2017, 7 patients in group A and 15 patients group B were included. Males represented 86% of both groups. Mean patient age (years) and body mass index (BMI) were 46.4 ± 7.6, 27.2 ± 6.9 vs. 43.1 ± 6.9, 25.6 ± 4.2 in groups A and B, respectively. Most common indications of SBN were abdominal discomfort and pain (100%); surgeons indicated loss of abdominal domain (57%), early satiety (28%) and hematuria (28%). All patients received kidney from living donors. Mean operative time and estimated blood loss were 379.8 ± 24min, 130.7 ± 15 vs. 464 ± 30 ml, 170 ± 10 in groups A and B respectively. Average length of stay(days) was 9.4 ± 1 and 7.8 ± 1.1 in groups A and B respectively. All patients had immediate graft function with average serum creatinine(mmol/l) on discharge, one month and last follow up were 85.6,78.6,81 vs. 77 ± 17,84 ± 12,93 ± 8 in groups A and B, respectively. There was no mortality, rejections, wound complications, collections or reoperation in both groups. One year graft and patient survival in both groups was 100%. Conclusion:SBN and LDRT is an acceptable alternative to a conventional two stage procedure without added morbidity and without significant negative impact on patient and graft survival, obviating the need for a separate procedure.