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Cognitive impairment is a frequent consequence of stroke, The study aimed to measure effect nursing intervention on cognitive rehabilitation of elderly patients with stroke for improving their cognitive function , Quasi experimental research design were used in this study. It conducted at neuropsychiatric, physical medicine and rehabilitation departments and outpatient neurology clinics at Assiut University hospital. Convenient sample of elderly patients attending to the previous setting were included in this study during a period of one year from September 2011 to September 2012, their number were 75 elderly stroke patients aged 60 years and above, (study group, 35, control group, 35) . Six tools were utilized ,tool 1: Socio-demographic characteristics and questions about stroke tool II: Mini-Mental State Examination tool III: Digit Span tool IV: Logical memory tool V: Geriatric Depression Scale. Tool VI: Barthel Index scale. The main result of the present study revealed that a significant statistical difference was existed between both studied groups in relation to Min Mental State Examination (P-value = 0.000*). Conclusion: Application of training program about cognitive impairment of stroke elderly patients have significant therapeutic effect on cognitive function, and on activities of daily living. Recommendation: Routine use of screening assessment of cognitive impairment in every stroke patient for early detection, and Health education to the elderly patients and caregivers about the possible ways of prevention of recurrent stroke and ways for controlling of diabetes and hypertension