Introduction: Telogen effluvium (TE) is an abnormality of hair cycling that result in an abrupt onset of generalized shedding of telogen hairs from the scalp, with or without an entifiable trigger. Ferritin and vitamin D play an important role in hair follicle differentiation.

Background and study aim: Hepatitis C has more than liver disease, a panel of systemic manifestation has been linked to HCV. We aimed in this study to evaluate the prevalence of HCV among major chronic skin diseases in Egyptian patients; we also aimed to study the impact of age, gender, viral load, and the possible role of severity of liver injury between the infected patients and association with skin manifestation.