Genus Neurada belongs to family Neuradaceae that is a small family consisting of 3 genera and 10 species distributed within North Africa (Thabet, Youssef, El-Shazly, El-Beshbishy, & Singab, 2018). Neurada constitutes mainly desert plants which are widely spread in the Arabian Peninsula. Traditionally, they are considered by the Bedouin as edible medicinal herbs (Khurshid et al., 2019). Neurada procumbens L. is called Als'dan by the Arabs and it is a widespread desert plant in the deep sand of the Arabian Peninsula. It is a grey-green herb that covers the ground like carpets and has a depth of roots of about 20 cm. Its leaves are relatively thick, its wavy ends, the diameter of its stem is about 1 cm, and its fruits are a disk with a diameter of 1-1.5 cm, coarse and spiky above, smooth at the bottom, and this usually remains as a rule around the main stem

Lobularia libyca (L. libyca) is a traditional plant that is popular for its richness in phenolic compounds and flavonoids. The aim of this study was to comprehensively investigate the phytochemical profile by liquid chromatography, electrospray ionization and tandem mass spectrometry (LC-ESI-MS), the mineral contents and the biological properties of L. libyca methanol extract. L. libyca contains significant amounts of phenolic compounds and flavonoids. Thirteen compounds classified as flavonoids were identified. L. libyca is rich in nutrients such as Na, Fe and Ca. Moreover, the methanol extract of L. libyca showed significant antioxidant activity without cytotoxic activity on HCT116 cells (human colon cancer cell line) and HepG2 cells (human hepatoma), showing an inhibition zone of 13 mm in diameter. In silico studies showed that decanoic acid ethyl ester exhibited the best fit in β-lactamase and DNA gyrase active sites; meanwhile, oleic acid showed the best fit in reductase binding sites. Thus, it can be concluded that L. libyca can serve as a beneficial nutraceutical agent, owing to its significant antioxidant and antibacterial potential and due to its richness in iron, calcium and potassium, which are essential for maintaining a healthy lifestyle.