Hyaluronic acid is a polymer with many biomedical applications with high production costs if obtained by fermentation. However, the use of agroindustry byproducts can improve the commercial viability. The aims of this work were to optimize the production of hyaluronic acid by Streptococcus zooepidemicus in sugarcane molasses medium supplemented with nutrients and to analyze the antioxidant and antimicrobial properties of hyaluronic acid. Hyaluronic acid production was greater in molasses (0.710 g•L -1 ) than in glucose (0.469 g•L -1 ). Only glutamine exhibited positive effects on production (0.843 g•L -1 ) in Erlenmeyer flasks. Using a bioreactor under 100 rpm agitation, production was three times greater than in flasks (2.55 g•L -1 ) and no differences were observed at higher agitation rates of 300 rpm. Hyaluronic acid produced presented with approximately 40 % (1 g•L -1 ) of antioxidant activity but did not show antimicrobial activity. Hyaluronic acid produced in molasses could be used in formulations as an antioxidant.

(CIP) (eDOC BRASIL, Belo Horizonte/MG) I34 Impactos das tecnologias nas ciências biológicas e da saúde 2 [recurso eletrônico] / Organizadora Christiane Trevisan Slivinski.-Ponta Grossa (PR): Atena Editora, 2019.-(Impactos das Tecnologias nas Ciências Biológicas e da Saúde; v. 2) Formato: PDF Requisitos de sistema: Adobe Acrobat Reader Modo de acesso: World Wide Web Inclui bibliografia

(CIP) (eDOC BRASIL, Belo Horizonte/MG) I34 Impactos das tecnologias nas ciências biológicas e da saúde 2 [recurso eletrônico] / Organizadora Christiane Trevisan Slivinski.-Ponta Grossa (PR): Atena Editora, 2019.-(Impactos das Tecnologias nas Ciências Biológicas e da Saúde; v. 2) Formato: PDF Requisitos de sistema: Adobe Acrobat Reader Modo de acesso: World Wide Web Inclui bibliografia