This paper investigates the steady, two dimensional, and magnetohydrodynamic flow of copper and alumina/water hybrid nanofluid on a permeable exponentially shrinking surface in the presence of Joule heating, velocity slip, and thermal slip parameters. Adopting the model of Tiwari and Das, the mathematical formulation of governing partial differential equations was constructed, which was then transformed into the equivalent system of non-linear ordinary differential equations by employing exponential similarity transformation variables. The resultant system was solved numerically using the BVP4C solver in the MATLAB software. For validation purposes, the obtained numerical results were compared graphically with those in previous studies, and found to be in good agreement, as the critical points are the same up to three decimal points. Based on the numerical results, it was revealed that dual solutions exist within specific ranges of the suction and magnetic parameters. Stability analysis was performed on both solutions in order to determine which solution(s) is/are stable. The analysis indicated that only the first solution is stable. Furthermore, it was also found that the temperature increases in both solutions when the magnetic parameter and Eckert number are increased, while it reduces as the thermal slip parameter rises. Furthermore, the coefficient of skin friction and the heat transfer rate increase for the first solution when the magnetic and the suction parameters are increased. Meanwhile, no change is noticed in the boundary layer separation for the various values of the Eckert number in the heat transfer rate.
In the present work, a series of 0, 1 and 7 wt% silver nano-particles (Ag NPs) incorporated poly lactic-co-glycolic acid (PLGA) nano-fibers were synthesized by the electrospinning process. The PLGA/Ag nano-fibers sheets were characterized using SEM, TEM and DSC analyses. The three synthesized PLGA/silver nano-fiber composites were screened for anticancer activity against liver cancer cell line using MTT and LDH assays. The anticancer activity of PLGA nano-fibers showed a remarkable improvement due to increasing the concentration of the Ag NPs. In addition to the given result, PLGA nano-fibers did not show any cytotoxic effect. However, PLGA nano-fibers that contain 1 % nano silver showed anticancer activity of 8.8 %, through increasing the concentration of the nano silver to 7 % onto PLGA nano-fibers, the anticancer activity was enhanced to a 67.6 %. Furthermore, the antibacterial activities of these three nano-fibers, against the five bacteria strains namely; E.coli o157:H7 ATCC 51659, Staphylococcus aureus ATCC 13565, Bacillus cereus EMCC 1080, Listeria monocytogenes EMCC 1875 and Salmonella typhimurium ATCC25566 using the disc diffusion method, were evaluated. Sample with an enhanced inhibitory effect was PLGA/Ag NPs (7 %) which inhibited all strains (inhibition zone diameter 10 mm); PLGA/Ag NPs (1 %) sample inhibited only one strain (B. cereus) with zone diameter 8 mm. The PLGA nano-fiber sample has not shown any antimicrobial activity. Based on the anticancer as well as the antimicrobial results in this study, it can be postulated that: PLGA nanofibers containing 7 % nano silver are suitable as anticancer- and antibiotic-drug delivery systems, as they will increase the anticancer as well as the antibiotic drug potency without cytotoxicity effect on the normal cells. These findings also suggest that Ag NPs, of the size (5-10 nm) evaluated in the present study, are appropriate for therapeutic application from a safety standpoint.
Corrosion of iron in sodium chloride (3.5% wt) solutions and its inhibition by ethanedihydrazide (EH) have been reported. Electrochemical impedance spectroscopy (EIS), cyclic potentiodynamic polarization (CPP), and change of current with time at −475 mV (Ag/AgCl) measurements were employed in this study. Scanning electron microscopy (SEM) and energy-dispersive X-ray (EDX) techniques were utilized to report surface morphology and elemental analysis, respectively. The presence of 5 × 10–5 M EH was found to inhibit the corrosion of iron, and the effect of inhibition profoundly increased with an increase in EH concentration up to 1 × 10–4 M and further to 5 × 10–4 M. The low values of corrosion current and high corrosion resistance, which were obtained from the EIS, CPP, and change of current with time experiments, affirmed the adequacy of EH as a corrosion inhibitor for iron. Surface investigations demonstrated that the chloride solution without EH molecules causes severe corrosion, while the coexistence of EH within the chloride solution greatly minimizes the acuteness of chloride, particularly pitting corrosion.
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