The aim of this study was to investigate the outcomes of self-medication in patients suffering from dyspepsia by comparing changes in the Health related Quality of Life before and after self-medication of dyspeptic disorders. Another study objective was the quantitative and qualitative analysis of the pharmacist's advice-giving to patients with dyspepsia. Therefore the impact of the counselling by the pharmacist on the patient's health outcomes was surveyed and compared between study and control pharmacies. Moreover, the study analysed the influence of a special training on the services provided by the pharmacies with regard to self-medication. A beneficial effect of self-medication on the HRQoL of patients with dyspepsia on a weekly basis has been detected in the study. There is evidence that advice-giving and counselling by the pharmacists in self-medication have a measurable impact on self-medication outcomes. Moreover, the study reveals that patients value the information provided by the pharmacist. Pharmacists gathered the relevant and comprehensive information from the patients having dyspeptic symptoms and provided advice concerning OTC-drugs. Moreover, pharmacists frequently discussed the relevance of factors aggravating dyspeptic disorders such as lifestyle, drinking, smoking, and manner of nutrition with the patient. Training programs and treatment guidelines for the pharmacist seem to obtain a positive effect on his performance. The findings of the study substantiate the value of a pharmacist-controlled self-medication. The study results suggest that the quality of primary health care in self-medication would improve if pharmacists' involvement were even more intense.

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