No abstract

No abstract

The design and fabrication of synthetic scaffolds to stimulate bone repair have been extensively researched and have experienced a remarkable increase in interest over the last decade. The aim of the current review is to systematically analyse the scientific evidence on osteogenic effectiveness of 3D printed polycaprolactone scaffold implanted with metallic bone regenerative compounds. To achieve the goal, this study conducted a systematic review of the global research published on 3D printed polycaprolactone scaffolds and a total of 338 were analysed by evaluating title, author and year, study design, sample size, groups, types of statistical methods used, outcome measures and inference. After excluding articles based on inclusion and exclusion criteria, a total of 5 articles were reviewed. The future trend is proposed by the systematic review and is discussed in the directions of biocompatibility, cell adhesion and proliferation, mechanical properties, gene expression, osteoblastic bone formation and graft degeneration. This study contributes by providing knowledge for practitioners and researchers to understand the state of the art of scaffold manufacturing with polycaprolactone with regenerative compounds and expose its research needs, which can serve both academia and industry.

Human bone is susceptible to damage from infections, fractures, and diseases. They do, however, have an amazing ability to repair themselves after being exposed to such factors, which is accomplished by a dynamic process of remodeling, maturation, differentiation, and regulated resorption. Larger defects, on the other hand, cannot be fully restored because their sizes exceed the capacity of the bones to repair. In such cases, medical intervention is required to stabilize, align, and support the damaged bone region so that lost function is restored. The goal of Bone Tissue Engineering is to incite and promote the natural healing process of bone, which does not occur in critical-sized defects. A biocompatible synthetic bone scaffold must be biodegradable to allow native tissue integration and must mimic the multidimensional hierarchical structure of native bone. Several biomaterials have been studied for their potential as bone scaffold materials, including ceramics, metals, polymers, and composites. Polymers, on the other hand, have emerged as the primary material in bone tissue engineering due to their tunable physiochemical properties, biocompatibility, and controllable biodegradability. This literature review provides insight into current trends in bone graft

The objective of this survey was to evaluate the knowledge, awareness, and practice of digital dentures among dentists. This is a cross-sectional survey conducted from January to February, 2022. Fifteen close-ended questions were framed and circulated among 150 dental practitioners and interns using an online survey form. The responses were collected and statistically analyzed. The results summarize that 95.3% were aware of digital dentures and 4.7% were not. About 60.1% do not use digital workflow, 27% do not have essential equipment, 9.5% were not confident in practicing digital dentures, and 3.4% found that it was inaccurate, showed poor retention, and a well-skilled technician was required. Most dental practitioners are aware of digital dentures. Among all practitioners with postgraduation were more aware of digital dentures than the interns and undergraduate practitioners. Most dentists do not practice digital dentures due to the high initial setup cost and maintenance. The majority of practitioners agree that digital dentures will be the ultimate tool in future dentistry.