Drugs are distinctive and sensitive products. It should pass specifi c tests and have specifi c criteria for human use. The disparity of any of the acceptance criteria will infl uence the product’s eff ectiveness, despite the product being still in validated expiry date. The stability study and manufacturing of many drugs were done at specifi c climatic zones, but marketed and sold at diff erent climatic zones. In a hot poor country or country that suff ers from a power supply shortage (like in Iraq), it is impossible to provide standard storage conditions as the manufacturer recommends. The research aims to study the eff ects of nonstandard storage conditions on the offi cial and non-offi cial acceptance criteria for stored tablets compared to the same newly manufactured tablets. The results showed that the physical appearance, tablet hardness, friability, disintegration, uniformity of weight, assay was not aff ected. On the other hand, the dissolution profi le of the stored products showed a change in the solubility behavior. From the results, we can conclude that storage conditions may not aff ect the content of the active substance. Still, it may aff ect other characteristics of the active substance, such as solubility. The research recommends the necessity of scrutiny of the storage conditions of drugs and not being lenient with them. Also recommends the necessity to study the dissolution profi le and stability of excipients when conducting a drug stability study and determining the expiry date.