BACKGROUNDTotal knee replacement is a surgical procedure in which parts of knee joint are replaced with artificial prosthesis so as to relieve pain and function of an arthritic knee. It is usually performed in geriatric patients under regional anaesthesia. In developing countries like India, majority of older population are overweight or obese according to standard body weight criteria. The aim of this study was to find out the association between body mass index and duration of spinal anaesthesia in adults undergoing total knee replacement arthroplasty.

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Background and Aims: The aim of this study was to evaluate the accuracy of non-invasive haemoglobin (SpHb) compared to laboratory venous haemoglobin (tHb) measurements among patients undergoing elective transurethral resection of prostate (TURP) surgery under spinal anaesthesia. Methods: In a prospective, observational, outcome-assessor blinded, cohort trial, we enroled 50 American Society of Anesthesiologists physical status (ASA-PS) I-II patients with benign prostatic hyperplasia. The primary outcome included SpHb and tHb measurements performed at four perioperative time-points: just before initiating the fluid preload (T1), and at 30 min (T2), 1 h (T3), and 2 h (T4) after starting the prostate resection, respectively. Statistical tool included intra-class correlation (ICC), Bland-Altman plots, and linear regression analysis. Results: We collected 200 SpHb/tHb data sets from 50 patients. The SpHb had a non-significant negative bias of –0.83 g/dL, –0.43 g/dL, –0.81 g/dL, and –0.46 g/dL, with limits of agreement of 2.6 g/dL to –4.2 g/dL, 2.4 g/dL to –3.3 g/dL, 1.3 g/dL to –2.8 g/dL, and 1.4 g/dL to –2.3 g/dL, for T1 to T4, respectively. The SpHb/tHb pairs correlated significantly (time-dependent increase in ICC from T1 to T4). The SpHb-tHb difference correlated significantly with corresponding serum sodium (T1 to T3), but not with perfusion index. No correlation existed between % change in SpHb-tHb difference (T1 to T4), and intraoperative blood loss or perioperative weight gain. Conclusion: The SpHb exhibited a clinically acceptable negative bias compared to tHb during TURP surgery. Although a wide limit of agreement between the SpHb/tHb pairs is a limitation, the real-time SpHb trends can still serve in clinical judgement.

A carotid cavernous fistula is an abnormal connection between the carotid artery and cavernous sinus which is a rare and sight threatening complication of craniofacial trauma. We report a case of a 36-year-old man with history of road traffic accident, flail chest, on mechanical ventilation who developed redness and progressive swelling of right eye. On evaluation, he was found to have right-sided conjunctival chemosis, pulsatile proptosis, and loud bruit on auscultation over right eyeball. Non-contrast computed tomography revealed multiple skull bone fractures with prominence of right-sided cavernous sinus and superior ophthalmic vein. Contrast enhanced magnetic resonance imaging with angiography revealed bulky cavernous sinus with tortuous right superior ophthalmic vein suggestive of right carotid cavernous fistula. Carotid cavernous fistula should be considered as a differential diagnosis for a critically ill patient with history of trauma developing swollen red eyes as the typical signs and symptoms cannot be assessed in patients on mechanical ventilation. The timely diagnosis and prompt treatment can save vision and can improve the outcome.