The current global death rate of Covid-19 is 2.1%. In Indonesia, the rate is 3.3%. The Muhammadiyah University General Hospital of Malang is a Covid-19 referral hospital and in July 2021 there were 242 Covid-19 cases admitted to the wards with 48 deaths (19.8%). This study aimed to determine the risk factors of death in Covid-19 patients in terms of comorbidities. This was an analytical retrospective observational study, which used secondary data from July 2021. Several risk factors were examined, including gender, age (26 to 86 years), length of treatment (1 to 17 days), and comorbidities (diabetes mellitus, hypertension, heart failure, renal disorders, obesity, pregnancy, stroke, COPD, etc). We concluded that the most influential risk factors were male gender, age between 60 to 69 years, treatment duration of 1 to 5 days and diabetes mellitus. Keywords: comorbidities, mortality, Covid-19, infection installation