Concrete in structures is likely to be exposed to high temperatures during fire. The probability of its exposure to elevated temperatures is high due to natural hazards, accidents and sabotages. Therefore, the performance of concrete during and after exposure to elevated temperature is a subject of great importance and interest to the designer. Popular normal strength grades of concrete produced by Ready Mix Concrete (RMC) India, Mangalore have been used in production of test specimens (150 mm cubes), cured and tested by destructive method for gathering data on strength characteristics. Later, these test samples were subjected to elevated temperatures ranging from 100°C to 800°C, in steps of 100°C with a retention period of 2 hours. After exposure, weight losses and the residual compressive strength retention characteristics are studied. Test results indicated that weight and strength significantly reduces with an increase in temperature. Residual compressive strength prediction equations are proposed for normal strength concretes subjected to elevated temperatures.
Background:
To evaluate mean metabolite ratios and Apparent diffusion co-efficient value with normalization in cerebral metastases using MRS in rural hospital setup in Central India.
Method:
A cross sectional hospital based observational study conducted over a time period of 2 years. All the cases registered with Acharya Vinoba Bhave Rural Hospital, Sawangi, Wardha, diagnosed on histopathological findings as cerebral metastases were included in this present study. All patients were examined on GE Brivo MRI machine with 1.5 Tesla magnetic field strength in the Department of Radiodiagnosis using b value of 1000 s/sq. mm, slice thickness 5mm, interslice gap 2mm applied in the x, y and z axes, central as well as peripheral portions of the tumor were manually sampled, preferably getting rid of cystic or necrotic areas. Histopathological diagnostic acumen was augmented with ADC values with normalization.
Result:
Range of ADC values observed was from 0.683 10-3 mm2/s to 0.873 10-3 mm2/s. Normalized ADC values were calculated on basis of observed ADC values and were in range of 0.8537510-3 mm2/s to 1.09125 10-3 mm2/s. Mean ADC value was calculated as 0.749 x 10-3 mm2/s. Mean normalised ADC value was calculated to be 0.9372 x 10-3 mm2/s. Observed metabolite ratios were derived from metabolic values obtained on MRS for Choline, Creatinine, Lipid lactate, myoinositol and n-acetyl aspartate. Range for Choline:Creatinine, Choline:n-acetyl aspartate, choline : myoinositol and choline : lipid lactate was 3.97 to 5.73, 3.24 to 5.76, 4.35 to 5.49 and 0.32 to 0.997 respectively. Mean values for Choline:Creatinine, Choline:n-acetyl aspartate, choline : myoinositol and choline : lipid lactate were 4.1289, 3.7838, 4.1256 and 0.9095 respectively.
Conclusion:
Research gap analysis towards which research question was framed stands filled up by the generated new knowledge in terms of 'Mean metabolite ratios','Apparent Diffusion Coefficient' and 'Normalised Apparent Diffusion Coefficient' values for cerebral metastases in the present study.
Metoclopramide hydrochloride is a widely used medication for the treatment of gastrointestinal disorders such as nausea, vomiting, and gastroparesis. However, it has been associated with extrapyramidal side effects (EPS) such as tardive dyskinesia, nystagmus, and other locomotive disorders on rare occasions. These reactions are commonly seen in children and females, particularly in young people. In this article, we report a rare case of a 15-week pregnant woman who was prescribed metoclopramide hydrochloride in view of nausea and vomiting, which was later diagnosed as vomiting in pregnancy not relieved with first-line medications, and has later developed drug-induced nystagmus, highlighting its unpredictable nature and shortcomings of management in the pregnant woman. This article will draw the attention of obstetricians and gynecologists to wisely prescribe metoclopramide hydrochloride for treating nausea and vomiting in pregnant women.
The pathologies of the male breast are often ignored due to its nonfunctional nature. A wide variety of benign and malignant conditions are seen in the male breast. The palpable abnormalities of the male breast must be particularly addressed so that accurate characterization and diagnosis can be made. We are presenting a case of bronchogenic carcinoma presenting with unilateral gynecomastia. Ultrasonography, mammography, and elastography imaging are described.
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