Dogs with previously sectioned dorsal spinal roots (T11-L3) were used in experiments for collecting the adrenal venous blood without anesthetizing or evoking any pain. Intravenous injection of histamine in doses of 0.05–1.0 mg/kg body wt. was demonstrated to produce a marked acceleration of 17-hydroxycorticoid secretion. The time courses of changes in the secretion rate after injection of varying doses of histamine are compared.
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