In our study, the greater frequency of restless legs syndrome, depressive symptoms, and fibromyalgia in the patients with migraine supports the role of dopamine, which is common to all three disorders. Interviews focused on these problems among migraine patients may help to decide on the best available treatment modality.
Ya z›fl ma Ad re si/Ad dress for Cor res pon den ce: Dr. Dürdane Aksoy, Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı, Tokat, Türkiye Gsm: +90 542 815 33 13 E-pos ta: dbekar @yahoo.com Ge liş ta ri hi/Re cei ved: 23.08.2011 Ka bul ta ri hi/Ac cep ted: 08.03.2012 © Arc hi ves of Neu ropsy chi atry, pub lis hed by Ga le nos Pub lis hing / © Nö rop si ki yat ri Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra f›n dan ba s›l m›fl t›r. ÖZET Amaç: İnme, tedavisindeki gelişmelere rağmen hala ciddi bir mortalite ve morbidite sebebidir. İnmenin erken döneminde hastanın ilk saatlerdeki nörolojik tablosu, görüntülemede saptanan lezyon büyüklüğü ve yaş en önemli prognostik faktörler olarak bilinmektedir. Bu çalışmada iskemik inmenin ilk saatlerinde glikoz, hemoglobin, hematokrit, beyaz küre (BK), ortalama eritrosit hacmi (Mean corpuscular volume: MCV), vitamin B12, folik asit, sedimantasyon gibi acil poliklinik şartlarında bakılabilecek, takip ve tedavi konusunda yönlendirici olabilecek prognostik belirteçlerin varlığını araştırdık. Yöntem: Bu retrospektif çalışmaya 2006-2011 yılları arasında hastanemize ilk 24 saat içinde başvuran 272 iskemik inmeli hasta alındı. Erken dönemdeki laboratuvar bulguları kaydedildi. Hastalar çıkış tarihlerindeki modifiye rankin skorlarına göre iyi ve kötü prognozlu grup olarak ikiye ayrıldı. Hastaların yaşları, laboratuvar sonuçları, hastanede kalış süreleri ve özgeçmişleri karşılaştırıldı. Bulgular: Hastalarımızda hipertansiyon inme risk faktörleri arasında ilk sırada idi. İyi ve kötü prognozlu gruplar arasında yaş, MCV, folik asit, BK ve sedimantasyon değerlerinde anlamlı farklılıklar vardı. Parametrelerin bağımsız değişkenler olarak lojistik regresyon analizi yapıldığında ileri yaş, yüksek MCV, düşük folik asit kötü prognozla anlamlı şekilde ilişkiliydi. Tartışma: İleri yaş inmede kötü pronozun en önemli belirtecidir. Yüksek MCV ve düşük folik asit düzeyleri de mortalite ve morbiditeyi etkilemişlerdir. Her iki parametre inme risk faktörlerinden biri olan hiperhomosisteinemi ile ilişkilidir. Dolayısıyla iskemik inmede erken dönemde homosistein, folik asit, vit B12, MCV düzeylerinin inme prognozuna etkisini araştıran prospektif çalışmalara ihtiyaç vardır. (Nö rop si ki yat ri Ar fli vi 2013; 50: 40-44) Anah tar ke li me ler: İskemik inme, prognoz, homosistein, folik asit Çıkar çatışması: Yazarlar bu makale ile ilgili olarak herhangi bir çıkar çatışması bildirmemişlerdir. ABS TRACTObjectives: Stroke, despite improvements in treatment is still a serious cause of mortality and morbidity. The most important prognostic factors of stroke are known as the neurological condition of the patient in first hours, the size of the lesion that imaging revealed, and the age. In this study, prognostic indicators such as erythrocyte sedimentation rate (ESR), folate, vitamin B12 (vit B12), mean corpuscular volume (MCV), white blood cell (WBC) count, hematocrit, glucose were investigated to help determining the course of the treatment. Method: In this retrospective study 272 ischemic stroke pati...
This study confirms the previous reports regarding the association of neuropathy with poor glycaemic control and duration of the disease. The association of neuropathy with retinopathy and hypertension is important.
Re cei ved/Ge liş ta ri hi: 21.09.2012 Ac cep ted/Ka bul ta ri hi: 30.12.2012 © Arc hi ves of Neu ropsy chi atry, pub lis hed by Ga le nos Pub lis hing/ © Nö rop si ki yat ri Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra f›n dan ba s›l m›fl t›r.
Aims. Peroneal neuropathy, meralgia paresthetica and tarsal tunnel syndrome are the most common entrapment neuropathies of the lower extremities. Although, the effect of Body Mass Index on the entrapment neuropathies of the upper extremities, especially carpal tunnel syndrome, has been studied extensively, its effect on the entrapment neuropathies of the lower extremities, except meralgia paresthetica which is well known to be associated with obesity, is not well understood. In this study, we aimed to investigate the relations between Body Mass Index and the common entrapment neurophaties of the lower extremities. Methods. This retrospective study focused on 204 patients that were referred to our electrophysiology laboratory with a pre-diagnosis of peroneal neuropathy, meralgia paresthetica, and tarsal tunnel syndrome. Each group is separated into two subgroups consisting of patients with and without entrapment neuropathy. Age, sex, and Body Mass Index values are compared amongst the groups. In addition, all of the patients with a pre-diagnosis of entrapment neuropathy are further divided into two subgroups based on their Body Mass Index as 'obese' and 'non-obese' patients, and type and frequency of entrapment neuropathies are investigated. Results. The mean age of the patients pre-diagnosed with entrapment neuropathy was 42.61± 13.75. There were 97 men and 107 women. Of the 100 patients that were verified to have entrapment neuropathy, 39 were diagnosed with peroneal neuropathy, 39 with meralgia paresthetica and remaining 22 with tarsal tunnel syndrome. 93.8% of the 'obese' patients who admitted with the pre-diagnosis of meralgia paresthetica were confirmed to have this diagnosis. Body Mass Index values of the patients with verified meralgia paresthetica were significantly higher than those of the patients who were found not to have meralgia paresthetica. There were no significant differences regarding Body Mass Index values between the patients with and without peroneal neuropathy or tarsal tunnel syndrome. Conclusion. It is suggested that meralgia paresthetica is related to high Body Mass Index and obesity. Very limited number of the past studies mentioned associations between high Body Mass Index and tarsal tunnel syndrome, and weight loss and peroneal neuropathy. In this investigation, no significant association was found between obesity or emaciation and peroneal neuropathy or tarsal tunnel syndrome. In addition, the rate of meralgia paresthetica was higher in patients with advanced age, but there was no significant relationship between advancing age and peroneal neuropathy or tarsal tunnel syndrome in this study. Keywords: Lower extremity, Body Mass Index, nerve compression syndromes ÖzetAmaç. Alt ekstremite tuzak nöropatileri arasında en sık olanlar peroneal nöropati, meralgia parestetica ve tarsal tünel sendromudur. Üst ekstremite tuzak nöropatilerinde özellikle karpal tünel sendromu ile Vücut Kitle İndeksi ilişkisi konusunda pek çok çalışma yapılmış olmasına rağmen alt ekstremitede obeziteyle i...
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