44T he most important prognostic factors for cervical cancer are tumor stage and size. Although not included in the International Federation of Gynecology and Obstetrics (FIGO) staging, the presence and extent of nodal involvement is an another important prognostic factor (1-3). The efficacy of magnetic resonance imaging (MRI) for the assessment of parametrial involvement (which is important in the primary treatment) of cervical carcinoma is widely recognized. Furthermore, the high accuracy of MRI for evaluating tumor volume and lymph node involvement is well known. In women with stage IIIB cervical tumors, the rates of recurrence, persistent disease in the pelvis, or distant metastases are very different from those of stage IIB disease (4). There are a few reports with a limited number of patients with stage IIIB cervical carcinoma that describe the accuracy of MRI for the assessment of pelvic sidewall invasion by advanced stage cervical tumors (5, 6).The aim of the present study is to correlate clinical and MRI findings in patients with cervical carcinoma treated with radiation therapy (RT). Materials and methods Patient selectionThis analysis was performed at a single radiation oncology department between 1996 and 2005 and included 42 previously untreated patients with cervical carcinoma who were then treated with either radiation alone or concomitant chemoradiotherapy for definitive treatment. The histopathologic diagnosis was squamous carcinoma in 37/42 patients (87.5 %) and adenocarcinoma in 5/42 patients (12.5%). Median patient age was 54.5 years (range, 27-74).The staging workup implemented the FIGO staging system used by a team of radiation oncologists and gynecologic oncologists and was assessed with rectovaginal examinations under general anesthesia prior to RT. MRI was performed for all patients before the initiation of RT. MRI was performed at least 3 weeks after each biopsy and within 15 days before RT. At the conclusion of the external RT, just before brachytherapy, the response to treatment was once again evaluated under general anesthesia. MRI protocolMRI studies were performed using a 1.0-T (Magnetom Impact, Siemens, Erlangen, Germany) or 1.5-T (Magnetom Vision, Siemens) magnet system with a consistent imaging protocol. For this protocol, transverse and sagittal T1-weighted spin-echo (SE) images and transverse T1-weighted fat-saturated images of the pelvis were obtained before and after contrast enhancement with gadopentetate dimeglumine. Transverse and sagittal T2-weighted fast SE sequences of the pelvis were also obtained. Imaging parameters are summarized in Table 1. ABDOMINAL IMAGING ORIGINAL ARTICLE Correlation of clinical and MRI staging in cervical carcinoma treated with radiation therapy: a single-center experienceGülgün Engin, Seden Küçücük, Hatice Ölmez, Zehra Işık Haşıloğlu, Rian Dişçi, Işık Aslay MATERIALS AND METHODSForty-two patients with pretreatment IB-IVA cervical carcinoma were included in this retrospective study. Pre-and post-treatment MRI findings of the patients were reev...
Yaşam süresi uzadıkça pelvik taban bozuklukları ön plana çıkmakta, giderek artan tıbbı ve sosyal bir sorun haline gelmektedir. Kadınların % 10'undan fazlası yaşamlarının bir kısmında pelvik organ prolapsusu veya inkontinans için cerrahi operasyon geçirmekte, bunların % 30'u başarısızlık nedeniyle tekrar opere olmaktadır. Bu bölümde pelvik organ prolapsusu anatomik temeller ve patofizyolojik mekanizmalar ışıgında ele alınmış; anterior, posterior ve apikal prolapsus olarak anatomik kompartmanlara göre sınıflandırılmış, cerrahi tedavi metodları ele alınırken literatürdeki başarı oranları ve komplikasyonlar belirtilmeye çalışılmıştır.
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