Background:Colorectal cancer is a common type of cancer worldwide, including in Sudan. However, few studies have assessed its demographic, clinical and pathological patterns in the Sudanese population.Objective:To assess the demographic, clinical and pathological patterns in patients with colorectal cancer at National Cancer Institute, University of Gezira, Sudan.Methods:This retrospective, cross-sectional study analyzed the data of all colorectal cancer patients who presented to National Cancer Institute, University of Gezira, between January 2016 and December 2017. National Cancer Institute, University of Gezira, is one of the two National Cancer Institutes in Sudan and receives patients from across Sudan. The demographic, clinical and pathological information were extracted from the patients’ files.Results:A total of 163 colorectal cancer patients who presented to National Cancer Institute during the study period and met the inclusion criteria were included in this study. Most patients were aged >40–69 years (58.8%), were male (53.4%) and from Central Sudan (65.6%). About 44% of the patients were diagnosed 6–12 months from the disease onset and 26.8% after >12 months. Change in bowel habits (51.5%), rectal bleeding (42.3%) and abdominal pain (32.5%) were the most common clinical presentations. About 58% of the patients did not undergo per rectal examination during their initial presentation. Rectum was the most common site of tumor (58.9%), and the majority of patients had Grade I adenocarcinoma (50.3%). Duke's Class B (38%) and Class C (31%) were the most common stages of the patients’ tumor, and signet ring carcinoma was found in 4.9% of the patients.Conclusion:This study found that in Sudan, colorectal cancer patients most commonly present late after the onset of symptoms, with an advanced stage and aggressive pattern as well as the proportion of younger patients is high. Further, per rectal examination is often not performed during the initial presentation.
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