Surgical prophylaxis is one of the areas where antibiotics are used commonly. In this study it is aimed surgical prophylaxis appropriateness and determination of cost analysis in our hospital. The study was performed November 30-15, 2018. 108 patients who underwent surgery in general surgery, orthopedics and neurosurgery clinics have been included in this prospective study. Patient selection was based on the classification of clean and cleancontaminated. Demographics, features of the surgery, applied prophylactic antibiotics and surgical prophylaxis appropriateness were recorded in the forms. All patient information forms were evaluated by infectious disease specialists using the surgical prophylaxis guide. The costs of unnecessary antibiotics were determined. Mean age of 108 patients who underwent a surgical procedure was 52.4 years and 39.8% of the patients were male and 60.2% were female. Of the surgery procedures 75.9% (n:82) were clean and 24.1% (n:26) clean-contaminated. Preoperative 58.3% (63) unnecessary antibiotic prophylaxis was detected. Continuing prophylaxis at a prolonged time were used in 99 (91.7%) patients in the postoperative period. Cefazolin is the most commonly used agent for surgical prophylaxis. The cost of unnecessary and long-term antibiotic use was determined as ₺6983,69. In this study, the time of antibiotic prophylaxis were to be a big problem. Prophylaxis often starts very early and continues for days. The wrong practices in surgical prophylaxis lead to unnecessary antibiotics treatment to the patients  and also burden to the budget of the country.

AMAÇ: ‘‘Coronavirus Disease 19’’ salgını pandemi olarak etkisini tüm dünyada sürdürmekte iken; ülkemizde pandemik aşı uygulamaları 14 Ocak 2021 tarihinde başladı. Bu çalışmada; Afyonkarahisar Sağlık Bilimleri Üniversitesi COVID-19 aşı polikliniğinde SARS-CoV-2 aşı uygulaması yapılan kişilerin demografik özellikleri, aşılama öncesi riskli temas öyküleri ve pandemi aşılamaları konusundaki görüşlerinin değerlendirilmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Pandemik aşı uygulamalarının ilk başladığı dönemde; birinci doz pandemik aşı uygulaması yapılan kişilere 17 sorudan oluşan anket yüz yüze görüşme yoluyla uygulandı. Sağlık çalışanları A grubu, diğer katılımcılar B grubu olarak sınıflandırılıp, bu iki grubun aşı olmayı isteme nedenleri, pandemiden etkilenme durumları ve diğer cevapları karşılaştırıldı. BULGULAR: Çalışma periyodu içinde 3159 kişi aşılandı; 1682’si (%53) sağlık çalışanı olup A grubu, geri kalan1477 (% 47) kişi B grubu olarak değerlendirildi. A grubunun anlamlı olarak daha fazla bilimsel yayınlardan, B grubunun ise medyadan bilgi edindiği görüldü. Aşılanma nedenleri sorgulandığında; yakınlarına hastalık bulaştırmaktan korkma, aşı etkinliğine ve koruyuculuğuna inanma, kısıtlamalardan kurtulup normal yaşama dönme gerekçesi ile aşı olanların oranı, A grubunda B grubundan anlamlı olarak yüksek bulundu. SONUÇ: Bu çalışmanın en önemli sonucu, hastalığı ağır geçirme riski olan kişilerin aşı ile ilgili bilgilere sağlık çalışanlarına göre daha yüksek oranda medyadan ulaşması olup toplumun daha doğru kaynaklardan bilgilendirilmesi için tedbir alınması konusunda uyarıcı olmasıdır.

Background/Aim: The definitive diagnosis of COVID-19 disease is made by demonstrating the presence of SARS-CoV-2 in nasopharyngeal swab samples. In patients who present with COVID-19-like symptoms but are found to be PCR negative, lung tomography, physical examination, and specific laboratory findings can guide diagnosis and treatment. This study aims to retrospectively evaluate the clinical, laboratory, and radiological findings of patients who presented with Covid-19-like symptoms. but were found to be PCR negative. Methods: This study was planned as a retrospective cohort study. Patients hospitalized in the pandemic service of Afyonkarahisar Health Sciences University between 19 March and 30 September 2020 - who were PCR negative and defined as possible cases through diagnosis, treatment, and follow-up guidelines of the Republic of Turkey Ministry of Health, were included. Of these patients, those without radiological pulmonary involvement were defined as group A, and those with radiological pulmonary involvement were defined as group B. Clinical and laboratory findings of both groups were evaluated and compared. Results: In the lung tomographic examination of 238 patients in the study, 16.4% in group A without radiological lung findings and 83.6% in group B with signs of inflammation were identified. While common complaints were high fever and diarrhea in group A, cough and shortness of breath were significantly higher in group B. The most common comorbidities in both groups were hypertension and diabetes, respectively, while hypertension was found to be significantly higher in group B. There was no mortality in any patient without lung involvement, but there was no significant difference between groups in terms of mortality. Conclusion: These techniques can be used in PCR-negative patients presenting with COVID-19, for an estimation of patients with a severe prognosis with pulmonary tomography findings, symptoms, laboratory results, and accompanying disease at the time of admission. Determining parameters that identify at-risk patients during the early period may contribute to improving patient management and the appropriate use of limited resources.

We aimed to evaluate the clinical characteristics, laboratory and imaging findings, and outcomes associated with the severity of illness of patients admitted to our hospital with possible COVID-19 diagnosis. The patients admitted to our hospital with a possible diagnosis of COVID-19 between March 25 and December 3, 2020, were evaluated retrospectively. In terms of their clinical, laboratory, imaging findings, and mortality were compared between patients discharged and hospitalized with died and survivors. 12470 patients admitted to our hospital with a possible diagnosis of COVID-19 tested by SARS-CoV-2 RT-PCR. Of those tested, 3116 (24.9%) were positive. Of the patients, 2529 (81.2%) were discharged, 587 (18.8%) hospitalized, and 92 (3%) were died. In the comparison of discharged, and hospitalized groups, a significant difference was found in age, symptoms, comorbid diseases, chest CT, laboratory findings, and mortality (p< 0.05). In the comparison of survivor, and dead, the risk of mortality analysis showed similar characteristics. Older age, male gender, comorbidities, lymphopenia, thrombocytopenia, increased levels of CRP, NLR, D-dimer, ferritin, and chest CT findings were significant risk factors. Of the patients who died, 23 (25%) were female and 69 (75%) were male. The outbreak of COVID-19 is a significantly health problem. We were experienced with high numbers of COVID-19 cases and found that age, symptoms, comorbid diseases, chest CT, laboratory findings of inflammation are significant predictors for admission to hospital. Therefore, these risk factors should consider routinely for patients with a high risk of developing severe and critical diseases by clinicians.