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Hydrazinolysis of Dl-1,4-dibromo-1,4-dideoxy-chiro-inositol (3a), followed by catalytic hydrogenation and acetylation, afforded di-N-acetyl-tetra-O-acetyl-neo-inosadiamine-1,3 (6a) and -scyllo-inosadiamine-1,3 (7) in 18% and 24% yields, respectively. From the intact hydrazinolyzate of 3a, two new stereoisomeric 1,3-biimino-1,3-dideoxy-inositols (4a and 5a) could be isolated, and their structures were established by correlating to the corresponding inosadiamines. A similar hydrazinolysis of 3,6-di-O-p-tolylsulfonyl-muco-inositol (12) gave sole crystalline 1,3-biimino compound (13a), whose structure was followed from its conversion into known di-N-acetyltetra-O-acetyl-myo-inosadiamine-4,6 (14). PMR spectra of four 1,3-biimino compounds were discussed.

Durch Hydrazinolyse des chiro‐Inosit‐Derivats (I) werden die Verbindungen (IIa) und (IIb) gebildet.

Die vier Stellungsisomeren des Didesoxystreptamins (Ia)‐(IVa) werden hergestellt.