Optical Absorption and Photoluminescence (PL) Measurements: The LiPBO sample was prepared as a thin film on a quartz substrate by thermal evaporation at a rate of 0.2 /s at 5´10 ±6 torr. Optical absorption and PL spectra were measured by UV-vis spectrometry and IAE-PL-SYS-1 (Nanotech) equipped with a linear charge coupled device detector (Ocean Optics, S2000) and a Xenon lamp coupled with a monochromator. For the PL measurements, the excitation wavelength was fixed as 365 nm, with regard to the absorption spectrum.Fabrication and Characteristics of OELD: A 1:1 mixture of poly(ether imide) (PEI) and N,N¢-diphenyl-N,N¢-bis(3-methylphenyl)-[1,1¢-diphenyl]-4,4¢-diamine (TPD) were dissolved in chloroform to form a solution concentration of ca. 0.5 wt.-%. The solution was spun for ca. 1.5 min at 5000 rpm onto ITO glass, which had a seven-segment pattern on it, and subsequently dried at 110 C for ca. 1 h. The dried polyimide HTL film had a thickness of 375 as determined by a surface profiler (Tencor P-10). Next, LiPBO was thermally evaporated onto the polyimide HTL using a low-temperature effusion cell (EPI-30-M-LT). The evaporation rate, the temperature, the vacuum, and the film thickness were ca. 0.1 /s, 315 C, 5´10 ±6 torr, and 200 , respectively. A 3500 thick layer of Aluminum was deposited on the LiP-BO thin film by thermal evaporation at a rate of up to 5 /s. The evaporation rate and thickness were detected using a thickness monitor (Sycon Instruments STM-100/MF). The luminance±current density±voltage (L±J±V) characteristics of OELD were measured by IAE-OELD-SYS with an electrometer (Keithley 237), a calibrated photodiode, a diode array rapid scan analyzer (PSI DARSA-2000), and a candela meter (Minolta CS1000). The electroluminescent (EL) spectra were measured by a spectrophotometer (JOBIN-YVON-SPEX 270M) with a photomultiplier tube (PMT) as a detector and the IAE-PL-SYS-1 mentioned previously.The design of porous solids that can selectively and reversibly bind molecules has been the subject of much recent interest. [1] These highly specific interactions are critical in a range of important practical chemical technologies such as chemical sensing, [2±4] separations, [5] and catalysis [6] . The design of lamellar inorganic hosts such as clays, phosphates, phosphonates and modified thin films that exhibit molecular recognition features has recently been reviewed by Mallouk and Gavin. [7] In lamellar inorganic solids, guest molecules access intracrystalline binding sites via intercalation reactions. In most cases, inorganic intercalation reactions are unselective processes which are driven by either oxidation±reduction, ion-exchange, acid±base, or donor±acceptor reactions. The interlamellar gallery expands to accommodate the guest species resulting in little size-or shape-selectivity to the reaction. Here we report the use of a crystalline-ordered layered double hydroxide (LDH) that exhibits shape-selective intercalation. In addition, we have found that this remarkable shape selectivity can be controlled by alterin...

Objective: Oxycodone/acetaminophen is one of the most commonly prescribed medications for pain management in the emergency department (ED) despite its high abuse liability. Our objective was to determine whether oral immediate-release morphine is as effective and well tolerated as oral oxycodone/acetaminophen for pain relief in stable ED patients. Design: This is a prospective comparative study in which stable adult patients with acute painful conditions who had either oral morphine (15 or 30 mg) or oxycodone/ acetaminophen (5/325 mg or 10/650 mg) ordered for them at the discretion of a triage physician were recruited. Setting: This study took place in an urban, academic ED from 2016 to 2019. Participants: Seventy-three percent of the subjects were between the ages of 18 and 59, 57 percent were female, and 85 percent were African American. Most presented with abdominal, extremity, or back pain. Patient characteristics were similar between treatment groups. Interventions: Of the 364 enrolled patients, 182 were given oral morphine and 182 were given oxycodone/acetaminophen at the discretion of the triage provider. They were asked to rate their pain score prior to receiving analgesia and at 60 and 90 minutes after administration. Main outcome measures: We examined pain scores, adverse effects, overall satisfaction, willingness to accept the same treatment again, and the need for additional analgesia. Results: There was no difference in satisfaction reported by patients who received morphine versus oxycodone/acetaminophen: 15.9 percent vs 16.5 percent were very satisfied, 31.9 percent vs 26.4 percent were somewhat satisfied, and 23.6 percent vs 22.5 percent were not satisfied, p = 0.56. Secondary outcomes also showed no significant difference: net change in pain score –2 vs –2 at 60 and 90 minutes, p = 0.91 and p = 0.72, respectively; adverse effects 20.9 percent vs 19.2 percent, p = 0.69; need for further analgesia 9.3 percent vs 7.1 percent, p = 0.44; willingness to accept analgesic again 73.1 percent vs 78.6 percent, p = 0.22. Conclusions: Oral morphine is a feasible alternative to oxycodone/acetaminophen for analgesia in the ED.

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had LGE; two patients had focal at RV insertion points LGE and two patients had mid-wall LGE in the basal infero-lateral segments. Conclusion ALMS is associated with increases in ECV and progressive change in T1 values over time that reflects progression of diffuse interstitial fibrosis in asymptomatic adults. Cross-sectional studies have identified ECV as a biomarker of cardiovascular "vulnerability" but longitudinal tracking has the potential to highlight those at greatest risk. 136 BEYOND THE AORTA: EXPERIENCES OF NEUROVASCULAR IMAGING IN LOEYS-DIETZ AND VASCULAR EHLERS DANLOS SYNDROMECarolyn Smith*, Sarju Mehta, Nigel Burrows, Peter Martin, Rosemary Rusk. Addenbrookes Hospital; *Presenting Author 10. 1136/heartjnl-2016-309890.136 Introduction The vascular complications of inherited syndromes Loeys-Dietz (LDS) and Vascular Ehlers Danlos (vEDS) lead to significant morbidity and mortality. Current recommendations advocate head to pelvis screening for LDS, and to a lesser extent for vEDS as complications typically involve medium to large arteries. We reviewed the practice in our aortopathy Inherited Cardiac Conditions Clinic (AICC). In our institution these patients are managed by a multi-specialist approach including cardiologists, neurologists, vascular surgeons, chest physicians, dermatologists and geneticists. Methods Patients were identified through current attendance at AICC or discussion at the linked multidisciplinary team (MDT) meeting. Electronic notes and imaging were reviewed to determine clinical details, genetic diagnosis, screening offered and (neuro) vascular complications. Results 36 patients were identified. Of these: 14 had a genetic diagnosis of vEDS, 8 a genetic diagnosis of LDS, 4 were excluded (alternate genetic diagnosis e.g. Marfan's) and the remaining 10 had a suggestive clinical phenotype without a typical LDS/vEDS gene mutation and were reviewed alongside the LDS/vEDS population. Screening was performed with separate CT angiograms (arch to carotids and arch to iliacs) to obtain adequate image quality.Two patients had clinical neurovascular events (spontaneous dissection). To date neurovascular imaging has been offered to 27 of the 32 patients (82%). Of these, two patients declined screening, leading to 78% of the patient group being studied (25 of 32).