Introduction This is a review of the evidence on the use of photodynamic therapy in the management of bone lesions in spinal metastasis. Materials and methods The literature was searched for relevant articles and the results were examined. The search included ongoing trials that aim to tackle this disease. Results Eight studies were identified in the literature; none were applied on humans. Conclusion Photodynamic therapy is an effective modality in managing osteoblastic and/or osteolytic spinal bone metastasis. Evidence regarding the efficacy of this therapy suggests that it will have a leading role in interventional hard tissue oncology and thus we propose a technique for managing such pathology.

Introduction Photodynamic therapy, a minimally invasive oncological modality, has been in use for over 20 years. However, little clinical data is available on its non-oncological efficacy. Several laboratory-based trials on animals have suggested that this technology may be applicable as an antimicrobial therapy. In orthopaedics, where implants and metal work are placed in deep tissue planes, a potential risk of infection is treated very seriously. Infection not only increases patient morbidity and mortality but also the burden on healthcare system. Proposing a new modality that can instantly tackle this problem. This critical review discusses surgical site infections subjected to photodynamic therapy. Conclusion Surgical care should be state of the art with careful attention to strategies that avoid the development of SSIs. When SSI does occur, superficial and deep wound infections can be treated using PDT by applying topical photosensitiser to the area followed by light illumination.