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S, N co-doped graphene quantum dots (S,N-GQDs) coupled with P25 (TiO2) (S,N-GQD/P25) have been prepared via simply hydrothermal method. The as-prepared S,N-GQD/P25 composites exhibited excellent photocatalytic hydrogen generation activities, with a significantly extended light absorption range and superior durability without loading any noble metal cocatalyst. The photocatalytic activity of this composite under visible light (λ = 400–800 nm) was greatly improved compared with that of pure P25. This remarkable improvement in photocatalytic activity of the S,N-GQD/P25 composites can be attributed to that S,N-GQDs play a key role to enhance visible light absorption and facilitate the separation and transfer of photogenerated electrons and holes. Generally, this work could provide new insights into the facile fabrication of photocatalytic composites as high performance photocatalysts.

A self-consistent kinetic model based on relativistic Vlasov–Maxwell equations is presented for the generation of quasistatic spontaneous fields, i.e., both the quasistatic magnetic (QSM) field and the quasistatic electric (QSE) field, in intense laser plasma interaction. For the circularly polarized laser, QSM field includes two parts, the axial part Bz as well as the azimuthal Bθ; the QSE field Es, corresponding to the space-charge potential, forms a plasma density channel. For the linearly polarized laser, Bz is absent. Equations for Bz, Bθ, and Es are uniformly derived from one self-consistent model under the static-state approximation, which satisfies the conservation law of charge. The profile of the plasma density channel and the dependence of the peak QSM fields on the laser intensity are discussed. The experiment and simulation results are explained by the model. The predicted QSM and QSE fields are also observed in the three-dimensional particle simulation.

Cordycepol C, a novel sesquiterpene isolated from the cultured mycelia of Cordyceps ophioglossoides, contains a hydroperoxy group and is cytotoxic to HepG2 cells. So far, no sesquiterpenes have been found in the genus Cordyceps and it would be interesting to investigate the antitumor efficacy as well as the mechanism of action of this unusual sesquiterpene. In this study, we showed that cordycepol C induced apoptosis of the HepG2 cells without affecting the normal liver cell line L-02. Cordycepol C caused poly(ADP-ribose) polymerase-1 (PARP-1) cleavage and triggered the loss of mitochondrial membrane potential (Δψ m ) in HepG2 cells in a time-and dose-dependent manner, resulting in the nuclear translocation of apoptosis-inducing factor (AIF) and endonuclease G (Endo G). We also found that cordycepol C induced the expression of Bax protein, followed by its translocation from the cytosol to mitochondria in both wild type and p53 knockdown HepG2 cells. However, cordycepol C could not cause cleavages of procaspase-3, -8, and -9. Caspase activities were not increased and Z-VAD-fmk, a caspase inhibitor, could not prevent the apoptosis induced by cordycepol C. These findings indicate that cordycepol C induces caspase-independent apoptosis in HepG2 cells through a p53-independent and Bax-mediated mitochondrial pathway, leading to the nuclear translocation of AIF and Endo G. Our study provides the molecular mechanism by which cordycepol C induces apoptosis in hepatocellular carcinoma cells and indicates the potential use of cordycepol C as an antitumor agent.