Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses risks to pregnant women and their infants. The spread of misinformation about COVID-19 vaccination is a barrier to optimizing vaccination rates among women of childbearing age. We conducted an environmental scan to identify misinformation about COVID-19 vaccination, pregnancy, and fertility, and a review to identify evidence to refute misinformation and strategies to correct and prevent the spread of misinformation. Seven identified themes of misinformation are: the vaccine causes female infertility; can cause miscarriage; and can decrease male fertility; mRNA vaccines attack the placenta; pregnant and breastfeeding persons should not get the vaccine; the vaccine can change menstrual cycles; and vaccinated people can spread infertility symptoms to unvaccinated people. Strategies that can be implemented by social media platforms to help prevent misinformation spread and correct existing health misinformation include improving information regulation by modifying community standards, implementing surveillance algorithms, and applying warning labels to potentially misleading posts. Health services organizations and clinicians can implement health misinformation policies, directly recommend vaccinations, provide credible explanations and resources to debunk misinformation, educate patients and populations on spotting misinformation, and apply effective communication strategies. More research is needed to assess longer-term effects of vaccination among women of childbearing age to strengthen the defense against misinformation and to evaluate strategies that aim to prevent and correct misinformation spread about COVID-19 vaccinations.