Background: Osteoarthritis (OA) is an irreversible degenerative joint condition that causes pain and disability for around 10% of total population. Therapeutic exercise is the first line of treatment that can reduce pain, enhance physical function, improve quality of life as well as save time and cost. Aim of study: Was to evaluate the effect of implementing exercise program on pain and physical functions among patients with moderate knee osteoarthritis. Design: A quasiexperimental design was utilized. Setting: The study was conducted at the outpatient clinic of the