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Objective To evaluate ultrasound guidance effect in pain relief during intrauterine device (IUD) insertion. Methods Four different databases were searched from inception till June 2022. We selected randomized controlled trials (RCTs) that compared transabdominal ultrasound guidance versus traditional non‐guided IUD insertion among women undergoing IUD placement for contraception. We used Revman software during performing our meta‐analysis. Our primary outcome was the pain score during IUD insertion as evaluated by the Visual Analog Scale (VAS). Our secondary outcomes were the procedure insertion time, satisfaction, and incidences of complications and misplaced IUDs. Results Seven RCTs were retrieved with a total number of 1267 patients. There was a significant reduction in the VAS pain score during IUD insertion among the ultrasound‐guided group (MD = −1.91, 95% CI [−3.08, −0.73], P = .001). The procedure insertion time was significantly shorter within the ultrasound guidance group compared with the control group (MD = −1.35, 95% CI [−1.81, −0.88], P < .001). Moreover, more women were significantly satisfied with the procedure among the ultrasound‐guided group (P < .001). In addition, ultrasound‐guided IUD insertion was linked to significant decline in incidences of complications and misplaced IUDs. Conclusion Ultrasound guidance can be used as a modified technique during IUD insertion as it decreases pain, procedure time, and rates of complications and misplaced IUDs with better patient satisfaction.

Background: Schizophrenia is one of the most serious and debilitating psychiatric disorders. that cause basic changes within the human brain. Objective: to evaluate MRI brain changes in patients with psychotic disordersMethodology: This cross sectional study was conducted on 50 patients aged from 15-40 years of both sexes. The patients were recruited from Al-Azhar University hospitals all of them were applied to Complete psychiatric history and examination, Structured Clinical Interview for DSM-IV (SCID-I), Positive and Negative Syndrome Scale(PANSS), Wechsler Adult Intelligence Scale, Brain magnetic resonance imaging. Results:In the current study, MRI brain changes among the studied group were 40%.There was also no measurable critical relationship (p-value > 0.05) between MRI results and the following parameters (age, positive scale, general scale, duration of disease and duration of treatment). Statistically significant correlation(p-value < 0.05) between MRI brain results and negative scale and total PANSS was present. Conclusion:There is a relation between psychotic disorders such as schizophrenia and MRI brain changes. Patients with negative symptom are more inclined to have brain changes. Antipsychotic medication has no role in brain changes in schizophrenia with no difference between first generation antipsychotic and second generation antipsychotic.