This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:To assess the e ectiveness and safety of antidepressant drugs in comparison with any other treatment (psychological, psychosocial, or pharmacological), placebo, or treatment as usual for PND.

pub2 (see www.thecochranelibrary. com for information). Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the review. We thank the Cochrane Review Group for their support in publishing these reviews.

Commissioner visits are routinely used in the NHS; however, their role in improving vaccination services is unknown. This study will evaluate the impact of immunisation commissioner visits to general practice and share the lessons learnt. This study analysed data from 262 practices across London between October 2015 and April 2016. Semi-structured interviews with the immunisation commissioners about the process was also undertaken. We found that commissioners saw the process as time consuming (the team spent a total of 11 weeks in a 6-month period conducting visits) and that adhering to a formalised process was challenging. However, it was a catalyst for developing better working relationships and identifying previously unknown service issues such as workforce shortages, high population turnover, and high rates of migrants with incomplete or unknown immunisation status. Further research on the effectiveness of commissioner visits is therefore warranted.

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:To assess the e ectiveness and safety of antidepressant drugs in comparison with any other treatment (psychological, psychosocial, or pharmacological), placebo, or treatment as usual for PND.

Advances in paediatric care mean that more children with complex medical problems (heart disease, neurodevelopmental problems and so on) are surviving their early years. This has important implications for the design and delivery of healthcare given their extensive multidisciplinary requirements and susceptibility to poor outcomes when not optimally managed. Importantly, their medical needs must also be understood and addressed within the context of the child and family’s life circumstances. There is growing recognition that many other factors contribute to a child’s complex health needs (CHNs), for example, family problems, fragmentation of health and care provision, psychological difficulties or social issues.To facilitate proactive care for these patients, we must develop accurate ways to identify them. Whole Systems Integrated Care—an online platform that integrates routinely collected data from primary and secondary care—offers an example of how to do this. An algorithm applied to this data identifies children with CHNs from the entire patient population. When tested in a large inner-city GP practice, this analysis shows good concordance with clinical opinion and identifies complex children in the population to a much higher proportion than expected. Ongoing refinement of these data-driven processes will allow accurate quantification and identification of need in local populations, thus aiding the development of tailored services.