Essentials• Little is known about the hemodynamic consequences of deep venous obstructive disease.• We investigated pressure changes in 22 patients with unilateral postthrombotic obstruction.• Common femoral vein pressure significantly increased after walking, compared to control limbs.• Common femoral vein hypertension could explain the debilitating effect of venous claudication.

The GBS is superior compared with both Rockall scores in predicting the need for treatment in patients with suspected acute UGIH presenting at EDs in the Netherlands. Patients with a GBS of 2 or less form a subgroup of low-risk patients. These low-risk patients are eligible for outpatient management, which might reduce hospital admissions and healthcare costs.

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Stenting of post-thrombotic iliofemoral obstruction significantly reduces venous hypertension in the common femoral vein and correlates with an improvement in the quality of life. Larger studies with a broader range of degree of obstruction need be performed to assess whether pre-stenting pressure measurements can predict post stenting clinical success.