Phalaris minor Retz. is a major weed of wheat crop across many continents. It is highly competitive in nature and mimics the wheat morphology. Consideration is given to the eradication of isoproturon resistance Phalaris minor and management approaches designated to minimize the impact of resistance. For management of isoproturon-resistant Phalaris minor in wheat crop in the tarai region by alternate herbicides, a field experiment was carried out during the winter season of 2016-17 and 2017-18. The broadcasting of isoproturon resistant Phalaris minor seeds was done before sowing of wheat in field. Treatments included (T1) Pendimethalin @ 750 g a.i./ha, (T2) Pendimethalin+Metribuzin @ 750+210 g a.i./ha, (T3) Pendimethalin+Metribuzin fb mesosulfuron+Idosulfuron (RM) @ 750+210 fb 12+2.4 g a.i./ha, (T4) Pendimethalin+Metribuzin fb 'Clodinafop+Metsulfuron-methyl'(RM) @ 750+210 fb 60+4 g a.i./ha, (T5) Pendimethalin fb Clodinafop propargyl @ 750 fb 60 g a.i./ha, (T6) Pendimethalin fb 'Clodinafop+Metsulfuronmethyl'(RM) @ 750 fb 60+4 g a.i./ha, (T7) Pendimethalin fb Mesosulfuron+Idosulfuron (RM) @ 750 fb 12+2.4 g a.i./ha, (T8) 'Clodinafop+Metsulfuron-methyl'(RM) @ 60+4 g a.i./ha, (T9) Mesosulfuron+Idosulfuron (RM) @ 12+2.4 g a.i./ha, (T10) Weedy. There was no phytotoxicity of any of the herbicide treatments on crop during both the years. The tank-mix or sequential application of herbicides would be a better option than their applications alone to manage the serious problem of herbicide-resistant P. minor in wheat.