Background: Fatigue is the most common symptom in patients with breast cancer undergoing chemotherapy. Benson’s relaxation technique is considered effective to reduce fatigue, but its effect in combination with smartphone technology is limited. Objective: This study aimed to analyze and determine the effect of the Benson relaxation application (Bens app) on fatigue in patients with breast cancer undergoing chemotherapy. Methods: A quasi-experimental design with a pretest-posttest comparison group was used. Fifty-six patients were included using consecutive sampling technique, of which 28 were assigned to the experimental group (received Benson relaxation technique using Bens app) and comparison group (obtained Benson relaxation technique using booklet). The Benson relaxation was done two times per day for seven days, and the Brief Fatigue Inventory questionnaire was used to measure the patients’ fatigue levels. Data were analyzed using paired and independent t-tests. Results: The experimental group (p = 0.001) and the comparison group (p = 0.015) showed a significant reduction in fatigue after receiving the Benson relaxation for seven days. However, there was a statistically significant difference in fatigue between the experiment and comparison groups after the intervention (t55 = 2.481, p = 0.016). Conclusion: Benson relaxation could reduce fatigue in patients with breast cancer using the Bens app and booklet. However, the Bens app is considered more effective than a booklet. Therefore, the Bens app can be viewed as an alternative to help patients perform Benson relaxation and integrated into the nurse palliative care program for patients with cancer.

Diabetes mellitus is not treated immediately can cause ineffective peripheral tissue perfusion. Ineffective peripheral tissue perfusion can lead to lower extremity amputation. Buerger allen exercise can improve ineffective peripheral tissue perfusion with an indicator of increasing the value of the ankle brachial index (ABI). This literature study aims to explore the intervention of Buerger Allen exercise on the ineffectiveness of peripheral tissue perfusion in patients with diabetes mellitus. This study uses a literature review method with 3 databases, namely Proquest, Google Scholar, and PubMed with a total of 6 articles reviewed with the PICOS framework criteria. The criteria for the articles used are those published from 2016 to 2021 amounting to 2,445 articles, then a selection is made based on duplicate titles, PICOS and critical appraisal to 6 articles. The administration of Buerger Allen exercise greatly affects the increase in the value of the ankle brachial index (ABI) as an indicator of the effectiveness of peripheral tissue perfusion in patients with diabetes mellitus. All reviewed articles show the same results. Buerger allen exercise can increase oxygen in the blood vessels so that it can be an alternative therapy that can be given to people with diabetes mellitus to improve ineffective peripheral tissue perfusion.