The use of cannabis for medical purposes is a controversial but an important topic of public and scientific interest. We report on the results of a self-administered questionnaire study conducted in the United Kingdom between 1998 and 2002. The questionnaire consisted of 34 items and included demographic data, disease and medication use patterns and cannabis use profiles. Subjects were self-selected; 3663 questionnaires were distributed and 2969 were returned [1805 (60.9%) women, mean age 52.7 years (SD 12.7)]. Medicinal cannabis use was reported by patients with chronic pain (25%), multiple sclerosis and depression (22% each), arthritis (21%) and neuropathy (19%). Medicinal cannabis use was associated with younger age, male gender and previous recreational use (p < 0.001). While caution must be exercised in interpreting these data, they point to the need for clinical studies of cannabis and cannabinoids with standardised and quality-controlled products.

This study examined the relationship between homophobia (defined as self-reported negative affect, avoidance, and aggression toward homosexuals) and homosexual aggression. Self-identified heterosexual college men were assigned to homophobic (n = 26) and nonhomophobic (n = 26) groups on the basis of their scores on the Homophobia Scale (HS; L. W. Wright, H. E. Adams, & L A. Bernat, 1999). Physical aggression was examined by having participants administer shocks to a fictitious opponent during a competitive reaction time (RT) task under the impression that the study was examining the relationship between sexually explicit material and RT. Participants were exposed to a male homosexual erotic videotape, their affective reactions were assessed, and they then competed in the RT task against either a heterosexual or a homosexual opponent. The homophobic group reported significantly more negative affect, anxiety, and anger-hostility after watching the homosexual erotic videotape than did the nonhomophobic group. Additionally, the homophobic group was significantly more aggressive toward the homosexual opponent, but the groups did not differ in aggression toward the heterosexual opponent.

The authors investigated the role of homosexual arousal in exclusively heterosexual men who admitted negative affect toward homosexual individuals. Participants consisted of a group of homophobic men (n = 35) and a group of nonhomophobic men (n = 29); they were assigned to groups on the basis of their scores on the Index of Homophobia (W. W. Hudson & W. A. Ricketts, 1980). The men were exposed to sexually explicit erotic stimuli consisting of heterosexual, male homosexual, and lesbian videotapes, and changes in penile circumference were monitored. They also completed an Aggression Questionnaire (A. H. Buss & M. Perry, 1992). Both groups exhibited increases in penile circumference to the heterosexual and female homosexual videos. Only the homophobic men showed an increase in penile erection to male homosexual stimuli. The groups did not differ in aggression. Homophobia is apparently associated with homosexual arousal that the homophobic individual is either unaware of or denies.Hostility and discrimination against homosexual individuals are well-established facts (Berrill, 1990). On occasion, these negative attitudes lead to hostile verbal and physical acts against gay individuals with little apparent motivation except a strong dislike (Herek, 1989). In fact, more than 90% of gay men and lesbians report being targets of verbal abuse or threats, and more than one-third report being survivors of violence related to their homosexuality (Fassinger, 1991). Although negative attitudes and behaviors toward gay individuals have been assumed to be associated with rigid moralistic beliefs, sexual ignorance, and fear of homosexuality, the etiology of these attitudes and behaviors remains a puzzle (Marmor, 1980). Weinberg (1972) labeled these attitudes and behaviors homophobia, which he denned as the dread of being in close quarters with homosexual men and women as well as irrational fear, hatred, and intolerance by heterosexual individuals of homosexual men and women. Hudson and Ricketts (1980) have indicated that the meaning of the term homophobia has been diluted because of its expansion in the literature to include any negative attitude, belief, or action toward homosexuality. Fyfe (1983) has also argued that the broad definition of homophobia threatens to restrict our understanding of negative reactions to gay individuals. Furthermore, Hudson and Ricketts criticized studies for not making the distinction between intellectual attitudes toward homosexuality (homonegativism) and personal, affective responses to gay individuals (homophobia). They indicated that many researchers do not state the operational definition of what they term homophobic. To clarify this problem, Hudson and Ricketts defined homonegativism as a multidimensional construct that includes judgment regarding the morality of homosexuality, decisions

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