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A letal case of angiosarcoma of the liver is reported. The 38 years old chemical laboratory assistant was exposed in vinylchloride medium about 3 1/2 years. The sarcoma metastasised into many other organs. This case is the fifth one reported in the German Federal Republic, in four of the cases the patient died. VC concentration at the work place was not measured. Thrombocytopenia observed in about 80% of the VC cases was not seen. There will be possibly observed further VC-caused tumors in the population. Nevertheless there might be other even extrahepatic VC-caused tumors in man, which could be concluded by animal experimental investigations.