Postpartum depression (PPD) is a significant mental health case after childbirth, distinguished by behavioral changes and emotional disturbance. PPD is a significant public issue estimated to affect 10–15% of women worldwide. The study's objective was to investigate whether low sera concentrations of vitamin D, calcium, and magnesium during the third trimester of pregnancy are associated with PPD. The study population included eighty pregnant women between the ages of 25 to 35 years. They were divided into two groups (control and depressed group). Simple samples technique collecting was used for serum collecting from the two groups. When the blood samples were taken, vitamin D level was determined using an ELISA device. Calcium and magnesium were measured by using the spectrophotometric method. A health questionnaire structure was used for screening depression after birth. After measuring pregnancy serum concentrations of vitamin D of (40) pregnant control and (40) pregnant with PPD, we found that there was no significant relationship between vitamin D concentrations and risk of PPD (p= 0.6497). Statistical analysis indicated the significant differences (p= 0.0003) between sera calcium levels of the control group as compared with the depressed group. Significant differences (p= 0.0005) in magnesium levels between the two groups were observed. Our study detected that vitamin D concentrations in the serum of women during their last trimester of pregnancy had no statistical link with their risk of PPD. Whereas direct associated with calcium and magnesium deficiency in the third trimester of pregnancy and the incidence of PPD were reported.

The serum levels of trace elements alterations have been linked with Type 2 Diabetes mellitus (T2 DM) and its complication. The Objectives of this study is to detect the correlation relation between serum Chromium, Magnesium (Mg), Zinc (Zn), Copper (Cu), and Iron (Fe) with Fasting Blood Sugar (FBS) in patients with type two diabetes mellitus, also to study the comparison of Ferroxidase, Transferrin, and Total iron binding capacity in patients with type two diabetes mellitus with control groups. A total of forty subjects were included in this study, they were divided in two groups (control and diabetic patients). Fasting blood samples were taken from all participants and analyzed for levels of Cr, Mg, Zn, Cu, and Fe. The concentration of serum trace elements of each sample was determined by using Inductively Coupled Plasma Optical Emission Spectroscopy. A negative correlation was found between Mg, Zn, and Fe level in Type-2 diabetics with FBS, whereas serum copper level shows significant positive correlation with FBS, and chromium shown no significant correlation with FBS. Ferroxidase, and Total binding capacity showed a significant increase, while a significant decrease was found in Transferrin of T2DM.