Sickle cell disease is an inherited hemoglobinopathy characterized by vaso-occlusive crises. Intraorbital hematoma secondary to hematopoietic medullary infarction is a rare complication of sickle cell disease. 1 The visual prognosis is at stake in the absence of immediate treatment. We report an atypical form of intraorbital hematoma revealed by bilateral exophthalmos in a sickle cell child; then, we will highlight the role of imaging in the diagnosis and management of intraorbital hematoma. | CASE REPORTA 15-year-old boy, known to have homozygous sickle cell disease, came for a consultation with headache and bilateral eye pain, which had been evolving for 2 weeks in a

A 75-year-old man with an aortic bioprosthesis was admitted with polyarthritis in a non-febrile setting. Blood cultures were positive for Listeria monocytogenes. The diagnosis of Listeria endocarditis and spondylodiscitis was evoked. These are two unusual forms of listeriosis.The evolution was favourable after antibiotic therapy.

Spontaneous bilateral intra-orbital hematoma is a rare complication of sickle cell disease in children. Imaging examinations are of paramount importance in the diagnosis and condition the management in order to avoid complications that can compromise the visual function prognosis.

Introduction: COVID-19 caused by SARSCov-2 could be serious and fatal. The objective was to determine the correlation of clinical, biological, CT and prognosis of severe COVID-19 according to the extent of lung lesions on the chest CT scan. Patients and method: This is a retrospective analytical study carried out in the department of pneumology University Hospital of the Joseph Raseta Befelatanana, Antananarivo, Madagascar for a three-month period from March to May 2021. Results: 78 severe COVID-19 cases met the inclusion criteria, for an incidence of 66.7%. The mean age of our patients was 52.81 ± 16.64 years. Age did not differ for the three CT extension groups (p = 0.60). Male gender, dyspnea, C-Reactive protein elevation correlated with the extent of lung damage (p <0.05). On CT scan, the ground glass image and bilateral involvement were also associated with CT extension of lung lesions (p = 0.03, p = 0.04). The prognosis in terms of mortality was worse in severe COVID-19 patients with disease greater than 26%. The overall death was 6.41%. Conclusion: Factors such as male gender, dyspnea, C-reactive protein, frosted glass and bilateral images of severe COVID-19 patients were correlated with the CT extent of lung lesions. Their understandings would make it possible to predict the unfavorable evolution of these lesions on a CT scan, thus reducing mortality.

Rendu Osler’s disease is a genetic disease characterized by mucocutaneous and visceral telangiectasias. Rendu Osler’s disease was discovered during hypoxemia during an outbreak of SARS-Cov2.This was a 36-year-old woman with exertional dyspnea and severe hypoxemia revealing pulmonary arteriovenous malformations on chest CT scan.