COVID-19 has become a pandemic. It affects multiple systems of the body including the nervous system. It invades the nervous systems through multiple routes - either olfactory tract, bloodstream (by binding to endothelial receptors) or via ACE-2 receptors in the brain. We report a case of Guillain-Barré syndrome (GBS) variant (acute motor axonal neuropathy (AMAN type)) associated with COVID-19 infection with positive polymerase chain reaction (PCR) test for COVID-19 and positive contact history with infected family member. GBS and its variants like AMAN can occur due to COVID-19 infection through its immune-mediated effects. Diagnosis of GBS should depend on the clinical and supportive criteria. The treatment should be started early to prevent progression and disease co-morbidities.

Iron deficiency anemia (IDA) accounts for roughly half of all anemia cases globally. Menorrhagia and menstrual cycle disorders render women of childbearing age more prone to IDA. One of the leading causes of menorrhagia is uterine fibroids (leiomyomas), which are defined as hyperplastic, usually benign, overgrowths of uterine wall muscle and connective tissue. This is a case report of a 45-year-old woman who came to the emergency department complaining of progressive fatigue and dizziness for two months. She was admitted as a case of life-threatening IDA with a hemoglobin level of 3.0 g/dL. She was ambulatory and hemodynamically stable without any features of severe anemia. Pelvic ultrasound was performed and revealed uterine fibroids. After partial correction of the anemia, she underwent a total hysterectomy as a definitive treatment.

Background: As of December 2020, the documented Corona Virus Disease 2019 (COVID-19) cases have almost reached 360,000 with a case fatality of 1.7%. In this study, we aimed to identify common presentations and complications of the disease and to assess the mortality predicting factors in hospitalized COVID-19 patients. Patients and Methods:A retrospective study was conducted between 1st June and 31st August 2020 on the confirmed cases of COVID-19 (using RT-PCR) admitted to King Khalid Hospital, Hail, Saudi Arabia. Adult patients aged 18 years or older who were hospitalized for at least 24 hours with confirmed COVID-19 during the study period were included, while patients with an inadequate past medical history and who were still hospitalized were excluded. Data were collected, coded, and analyzed using SPSS software.Results: Out of 1466 patients tested by RT-PCR, 404 patients (27.55%) were positive for COVID-19. Out of these 404 patients, 131 (32%) were hospitalized and included in our study with a mean age of 57±16 years, and 74 patients (56.5%) were males. Out of 131 patients, there were 28 deaths (21.4%). The most frequent comorbidities were hypertension (80.9%), diabetes mellitus (67.9%), and chronic kidney disease (39.7%). Fever (95.4%), cough (80.9%), dyspnea (65.6%), and body aches & myalgia (35.9%) were the most common symptoms. The significant predictors of mortality were elevated levels of WBC (AOR= 24.2; p=0.06), BUN (AOR= 31.8; p=0.001), AST (AOR= 11.8; p=0.041), INR (AOR= 11.5; p=0.001), D-Dimer (AOR=10.7; 0.005), lactic acid (AOR= 38.3; p<0.001), and creatinine kinase (AOR=2.1; p<0.001). Decreased lymphocyte count and SPO 2 were associated with a high risk of mortality (AOR= 11.9; p=0.037 and AOR= 34.8; p=0.003), respectively. Similarly, patients with COPD were at high risk of mortality (AOR= 18.8; p=0.004). Conclusion:Among the included patients, the hospitalization mortality rate was 21.4%. Old age and male gender were associated with significant mortality. The independent predictors of COVID-19 mortality were COPD, SPO 2 <89, acute Liver Injury, leukocytosis, lymphopenia, and markers of inflammation (ESR, CRP, D-Dimer) and shock (lactate, and creatine Kinase). Further studies are needed to assess definite mortality predictors in hospitalized COVID-19 patients to identify and guide patients' management at risk.