Background: The coronavirus pandemic which had its origin in the Wuhan China has been spreading across the globe with far reaching complications and a variable clinical course. A variation of the laboratory parameters during the disease course remains a constant parameter to monitor the disease course and progression. Since the laboratory parameters are standardized globally, these may also act as uniform guidelines for the patients monitoring and treatment. Aims and Objectives: The aim of the study was to serial charting of the laboratory parameters in the recovered and expired patients of COVID-19 and to determine an associated prognostic significance. Materials and Methods: A retrospective observational study from the laboratory and medical records was conducted on the patients admitted from March 17, 2020, to May 31, 2020, at the tertiary care center dedicated to the treatment of RT-PCR confirmed COVID-19 positive patients. Results: The group of parameters showing a poor prognosis include a rising WBC count, high neutrophilic percentage, low lymphocyte percentage (<10) an NLR > 15, low lymphocyte monocyte ratio < 3, rising blood urea nitrogen, serum creatinine levels, and serum electrolyte levels. The liver function tests variation reflecting a poor metabolic activity of the liver, namely, a low serum albumin and albumin globulin ratio, rising SGOT levels, and total bilirubin levels. A highly significant variation in the acute phase reactants showing an exponential rise such as the serum lactate dehydrogenase levels, serum ferritin, fibrinogen, C-reactive protein, and IL 6 levels an increased level of D Dimer (>3) and a prolongation of the APTT. Conclusion: The variation of the laboratory parameters acts as a fair marker for the disease progression. Since the disease shows a variable progression with a sudden worsening of the clinical symptoms, a comprehensive monitoring of the laboratory parameters serves to diagnose and treat the disease progression.

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Background: Through the years, breast cancer management evolved toward conservation surgery. It is obvious that the clinical management requires a multidisciplinary approach to restoration of activity if daily living and quality of life after modified radical mastectomy. Aims and Objectives: The objectives of the study were to measure pain after physiotherapy intervention, to measure chest expansion after physiotherapy intervention, and to measure and improve shoulder range of motion (ROM) after physiotherapy intervention. Materials and Methods: This was a cross-experimental study in which initial data were recorded from the medical records, and then, after assuming proper resting status of the patient, the patients were assessed first numeric pain rating scale (NRS) for pain, ROM of shoulder joint, and chest expansion before and after the physiotherapy treatment given till patient get discharged. Results: In the present study, a total of 7 participants were included who fulfilled inclusion criteria. All the participants underwent routine physiotherapy treatment started from the day 1 till discharged, and NRS for pain, ROM of shoulder joint, and chest expansion all parameters were statistically significant (P < 0.005). Conclusion: The present study concluded that physiotherapy is more effective in modified radical mastectomy.

Osteoarthritis is not a single disease [1]. Osteoarthritis affects isolated Tibiofemoral compartment, isolated patellofemoral compartment or the both combined of them. Among various approaches to sub classification of knee osteoarthritis, European League against Rheumatism (EULAR) Task Force recognized subtype of compartmental distribution for diagnosis of osteoarthritis [2]. Traditionally, in cases of osteoarthritis of knee most of the research has focused on understanding of general osteoarthritis of knee or tibiofemoral osteoarthritis of knee. In fact, isolated patellofemoral osteoarthritis may not be so rare. Even though, the PF compartment is rarely considered in investigation of osteoarthritis. Need of the ReviewIdentifying the prevalence of the condition is a milestone for the identification of risk factors, these are directly related to the culture, ethnicity and the lifestyle they have and that makes it easy to decide on the treatment aspect. Current treatment paradigms for Patellofemoral osteoarthritis are inadequate. Furthermore, published guidelines are based exclusively on research utilizing Tibiofemoral osteoarthritis; there is no evidence for Patellofemoral arthritis. In many regions where data is lacking, in future we could have studies mentioning the prevalence rates and also determine the relevance of ethnicity.

Aims: To find the knowledge and attitude among physiotherapy interns towards physiotherapy and total knee replacement in case of osteoarthritis of knee. Material and Methods: A cross-sectional observational study was carried out using a structured questionnaire. The structured questionnaire was designed to assess the knowledge and attitude among physiotherapy interns towards physiotherapy and total knee replacement in case of osteoarthritis of knee across the colleges in Gujarat. The data was analyzed by using the Statistical Package for Social Sciences (SPSS) statistical software, version 16. Results: Total 250 Interns students were participated in the study. Majority of Physiotherapy students believed 75-100% successful in improving functional mobility. Physiotherapy is effective in mild and moderate stage of osteoarthritis knee. Physiotherapy was considered as an alternative to total knee replacement by 85% of Interns, and they think that it can delay or avoid total knee replacement in patient with minimal symptoms, and if patient with minimal symptoms are advised for total knee replacement then they take an effort as to discuss with the orthopedic surgeons to take physiotherapy as first treatment option. Conclusion: Interns knowledge and attitude on Physiotherapy for osteoarthritis knee concludes that physiotherapy is effective in mild to moderate stage of osteoarthritis knee for improving functional mobility .Their opinion for advising criteria of total knee replacement to the individual having NPRS 8-10, Flexion range of motion restriction of 45-90 degrees, Extension range of motion restriction 0-45 degrees, Fixed flexion deformity, Medial Instability and ADL's affection i.e. Getting out from chair, sit to stand, crossed leg sitting, squatting etc.