Complementing
the demand for effective crime reduction measures
are the increasing availability of commercial forensic “taggants”,
which may be used to physically mark an object in order to make it
uniquely identifiable. This study explores the use of a novel “peptide
coding” reagents to establish evidence of contact transfer
during criminal activity. The reagent, containing a fluorophore dispersed
within an oil-based medium, also includes a unique synthetic peptide
sequence that acts as a traceable “code” to identify
the origin of the taggant. The reagent is detectable through its fluorescent
properties, which then allows the peptide to be recovered by swabbing
and extracted for electrospray ionization-mass spectrometry (ESI-MS)
analysis via a simple liquid–liquid extraction procedure. The
performance of the reagent in variable conditions that mimic the limits
of a real world use are investigated.
complicated by tamponade requiring pericardial drain. 2% of procedures were complicated by stroke; one cerebellar stroke with full recovery and one hemiplegic stroke with residual right arm weakness and mild dysphasia. 1 patient developed post procedural pericarditis. There were no cases of significant vascular access site bleeding. Conclusion: This series demonstrates the learning curve involved with commencement of performing AF ablation procedures. The procedure carries significant risks as demonstrated and is therefore only recommended for patients with symptoms refractory to antiarrhythmic therapy.
significant bradycardias where a permanent pacing decision needed to be delayed. The majority of implants (15/27) were for durations of < 6 weeks (mean 4), the longest implant being 21 weeks. One lead dislodged during cardiac surgery, one lead was damaged during dressing change, requiring replacement. No systemic infections occurred. No other complications were observed during implant duration or with removal. 17/27 subsequently underwent permanent device implantation (4 ICDs), with 6 patients not needing further device support. Four patients remain implanted, one at 12 weeks duration. Conclusion: Temporary pacing can be provided for prolonged periods without complications and is a feasible option when permanent implantation needs to be delayed.
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