Lipoid proteinosis (LP) is a rare autosomal recessive disorder characterized by the deposition of amorphous hyaline material in the dermis and submucosal connective tissue. To date <500 cases of LP have been described and oral manifestations described in a very few reports. Indian cases are much less reported and reviewed. Hence, here review of 51 Indian LP cases along with a case of histologically proven LP in 12-year-old male patient with typical skin, ocular, laryngeal, oral and radiographic features is done. Cases from 1969 to 2021 were collected using keyword LP on google and google scholar and Indian cases were analyzed afterward. Review with case presentation regarding oral manifestations will help the oral physician to diagnose LP in early stage.

Oral submucous fibrosis (OSMF) is a chronic progressive, scarring disorder of oral cavity, which includes buccal mucosa, tongue, lips, anterior faucial pillars, soft palate, and oropharynx. Changes in soft palate morphology will start even before the OSMF, present itself clinically. These changes can lead to sleep apnea, difficulty in speech, swallowing & respiration. Various radiographs are good diagnostic aid to assess the soft palate and its morphology or any changes in morphology. To evaluate and compare soft palate morphology and dimensions in various stages of OSMF with control by radiographic evaluation.: 60 patients were evaluated and compared for soft palate morphology, its length, width and angle by using lateral cephalogram and Cone beam computed tomography (CBCT). Most common type of soft palate was found to be type 1 (leaf shaped) in both groups as well as by both radiographic techniques. Significant decrease in length and increase in width with increasing grades of OSMF group. As per p value CBCT gave more precise result. As the OSMF progresses soft palate becomes stout and bulky and significant changes occur in soft palate dimensions and are better evaluated by CBCT. As involvement of the soft palate is the earliest change to be noticed, radiographs should be used as one of the diagnostic aids in OSMF patients.

Malignant melanoma arises from melanocytic cells. Oral mucosal melanoma is a rare malignancy with the tendency to metastasize and locally invade tissues more readily than other malignant tumors of the oral cavity. Here, a very rare entity of the pigmented nodular variety of the oral malignant melanoma of maxillary buccopalatal gingiva with regional lymph node involvement and distant metastasis to the lungs is reported. A new proposed clinical classification of oral malignant melanoma is explained. Early detection is very important for a better prognosis.