INTRODUCTIONAlthough Indian traditional system of medicine being the quondam system of health care, yet its acceptance is parochial to south-east Asia only, especially in India.1 It has to cover a long distance to find its place in modern world. In last five decades, good percentage of literary research has been done in this field and further requirement is to develop new strategies for research while keeping in mind the bedrocks of Indian traditional system of medicine.2 Moreover, implementation of 'Pharmacovigilance' in Ayurveda plays an important role in optimizing drug safety and improving treatment outcomes. 3The traditional literature of medicine (Ayurveda) is overflowing with the treasure of several herbal as well as herbo-mineral preparations. Narikela Lavan and Kajjali, both are herbo-mineral compounds delineated in various classical Ayurvedic texts. Narikela Lavan consists of two ingredients-Narikela and Saindhava Lavan. Narikela is the sanskrit name of coconut (Cocus nucifera linn) and that of Saindhava lavan is rock salt (Sodi chloridium). Coconut is a drug of plant origin and rock salt is from mineral origin. Thus, Narikela lavan is a herbomineral preparation. Coconut (Cocus nucifera linn.) belongs to the family Arecaceae (palm family). It is a vast family having around 217 genera and 2500 species. Cocos nucifera belongs to the order arecales and it is the only species of the genus cocos belonging to the subfamily cocoideae, which has 27 genera, and 600 species. 4 Five different types of salts are mainly used in several Ayurvedic preparations. Most commonly used and best form among them is Saindhava Lavan. It is a mineral that is composed chiefly of sodium chloride. Chloride and sodium ions are the two major elements of salt. 5Kajjali is a commixture of mercury and sulphur in varing ratios. The impotance of kajjali lies in the facts that mercury cannot be consumed in its natural form and also it is very difficult to convert mercury into powder form in atmospheric conditions. Therefore, kajjali forms the basic component of maximum herbo-mineral formulations. It gives the structural and functional stability to the formulations. 6 MATERIALS AND METHODS Synthesis ProcedureNarikela Lavan-Mature fruit of coconut was taken and its outer fibers were removed. A hole was through an eye of the coconut and its water was removed completely. Then finely powdered rock salt was filled into it through the eye only. The hole was then sealed with mud and whole of the coconut was covered with the layer of thin cotton cloth impregnated with mud. When dry, it was subjected to the heat of around 1000 0 C temperature in a pit full of cow-dung cakes. In this way, a grayish black coloured ash of coconut and rock salt is obtained. This ash is known as Narikela Lavan which is used as enhancer of digestive power and cures hyperacidity. The temperature at which this formulation is prepared, activated charcoal is formed.7 Activated charcoal reduces the absorption of toxins and various drugs such as aspirin, acetaminophen, phenoba...