We conclude that infarct expansion and scar shrinkage may be controlled by different factors. In addition, we conclude that measurement of systolic wall thickening alone is not always adequate to assess postinfarction regional contractile function.

These results indicate the presence of marked subendocardial edema 2 days after reperfusion following 2 to 4 hours of coronary occlusion. At 3 months after reperfusion, however, there was volume loss in the inner wall due to shrinkage along the myofiber direction with reduced transmural function and loss of longitudinal shortening, while both tissue volume and function recovered completely in the outer wall.

No abstract

Probucol administration of 4 weeks produced torsades de pointes associated with exacerbated QTinterval prolongation in a 36-year-old womanwith Romano-Wardsyndrome. With discontinuance of probucol, the QTinterval corrected for rate shortened from 620 msec to 500 msec and ventricular ectopic beats disappeared completely. Although probucol is known to prolong the QTinterval, associated ventricular tachyarrhythmia has not been reported in humansas yet. This case suggests that one should be very careful in the administration of probucol to patients with long baseline QT intervals.