Aim: This study aimed to evaluate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in elderly patients with Stage I-III colon cancer for long-term oncologic outcomes. Patients and Methods: We retrospectively reviewed 175 patients aged >75 years who underwent radical surgery for Stage I-III colon cancer between 2000 and 2015 at our institute. Overall survival (OS), cancer-specific survival (CSS), and relapse-free survival (RFS) were evaluated according to NLR values using propensity score analysis. Patients were allocated to the higher NLR (H-NLR) or the lower NLR (L-NLR) group with a cut-off value of 2.3, based on receiver operating characteristic curve. Results: Before case matching, there were significant differences between the two groups for CSS (p=0.023) and RFS (p<0.001), but not for OS (p=0.069). Similar results were obtained after case matching, with significant differences observed for CSS (p=0.003) and RFS (p=0.027), but not for OS (p=0.145). Conclusion: NLR may be a prognostic factor in elderly patients with colon cancer.Colon cancer surgery for elderly patients is becoming increasingly common as the elderly population continues to grow worldwide. There is usually no hesitation in deciding on a treatment plan for resectable colon cancer. However, elderly patients often have several comorbidities and dysfunctional status, which can result in higher morbidity and mortality after surgery compared with younger patients (1, 2), making decisions regarding treatment strategy difficult. Thus, it is important to assess the general condition of elderly patients preoperatively in order to predict long-term oncologic outcomes.There are various risk assessment tools to assess the general condition of elderly patients [e.g., American Society of Anesthesiologists' (ASA) class (3), Charlson comorbidity index (4), the National Institute on Aging (NIA) and the National Cancer Institute (NCI) (5), the sum of diseased organ systems (SDOS) ( 6)]. We previously reported that neutrophilto-lymphocyte ratio (NLR) is a prognostic factor for both overall survival (OS) and relapse-free survival (RFS) in Stage II-III colon cancer patients of all ages (7). However, there was no reports assessing NLR focused solely on elderly patients.In this regard, this study aimed to evaluate the prognostic value of NLR in elderly patients with Stage I-III colon cancer for long-term oncologic outcomes using propensity score analysis.Follow-up. The median follow-up period was 63.3 months (range=0.2-186.6 months). We followed patients who had Stage II
Hibernomas are extremely rare, benign tumors of brown fat origin with no specific symptoms. Surgery is the only treatment option, and because a definitive preoperative diagnosis is often not obtained, open surgery is usually chosen. In this case, we performed laparoscopic surgery on a 33-year-old woman with retroperitoneal hibernoma. As in most cases, a definitive diagnosis had not been preoperatively made; therefore, we laparoscopically removed the retroperitoneal tumor of unknown pathology as a diagnostic treatment. We chose laparoscopic surgery because of the magnifying effect of the laparoscope and to minimize scarring. The surgery was uneventful, with a procedure time of 280 minutes and a blood loss of 20 mL. The postoperative course was uneventful with no complications or recurrence. We conclude that laparoscopic surgery may be a viable option for hibernomas.
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