Polygala Root (the root of Polygala tenuifolia WILLDENOW; Japanese name "Onji"), a well-known crude drug, traditionally used as an expectorant and sedative, has been attracting increased interest in recent years owing to its newly found pharmacological effect related to neuroprotection. However, there is no specific method for identifying and estimating the quality of this crude drug in the Japanese Pharmacopoeia, 17th edition. Therefore, in order to develop a TLC-based simple and convenient identification method using characteristic chemical marker(s) for the drug and its extract products, UV-sensitive constituents of Polygala Root were first investigated. A total of 23 aromatic compounds were isolated and characterized. Two new compounds, namely, polygalaonjisides A (1) and B (2), were characterized as syringic acid 4-O-(2′-O-β-Dapiosyl)-β-D-glucoside and 2-O-(β-D-glucosyl)-3′-O-benzoylsucrose, respectively. Based on these phytochemical results, a TLC method focusing on three marker spots with Rf value of approximately 0.4-0.5 due to tenuifolisides A and B and 3,6′-di-O-sinapoylsucrose was proposed as a simple and convenient test to identify Polygala Root or its single-extract products on the market. The data presented in this paper could be useful in stipulating a confirmation test to identify Polygala Root.
To elaborate design concepts of elevated buildings in an area of drifting snow, snow deposition and wind profiles around two buildings at Syowa station, Antarctica, were observed in 1978. To interpret the observed results in detail, wind-tunnel experiments on scale models were carried out. A wind-scooped snow deposit was formed behind the building and a sharp ridge was formed on the lee side. The highest point of the deposit was at a distance of 1 or 1.5 times the floor height (about 1.5 m) and the skirt of the snowdrift extended about 5 times the height of the roof. Wind profiles measured near one of the buildings (ionosphere hut) were expressed in terms of the logarithmic law. Two methods based on wind-tunnel experiments were used to estimate the development of snowdrifts around the building: one is to estimate the deposition from the difference in transport of blowing snow calculated from wind profiles and snowdrift flux profiles, the other is by deduction from the distribution of wind profiles. These experiments together with previous ones indicated that the optimum floor height was about 44% of the height of the building.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.