The aim of this article is to report the recent surge in use of additive manufacturing (AM) or three-dimensional printing (3DP) services in healthcare, especially the field of orthopaedics. Pakistan’s healthcare infrastructure has been slow in adapting and implementing this new technology which is an integral part of the industry 4.0. Various sources including Pubmed, ScienceDirect, Google Scholar and Google were utilised from June to august 2021 to extract articles and information on advantages of AM in orthopaedics. Furthermore, its possible acquisition by a hospital, educational or an industrial setup is also highlighted in this review. doi: https://doi.org/10.12669/pjms.38.3.5182 How to cite this:Gandapur HK, Amin MS. Orthopaedics and Additive Manufacturing: The Start of a New Era. Pak J Med Sci. 2022;38(3):---------. doi: https://doi.org/10.12669/pjms.38.3.5182 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.