Sit-to-stand (STS) activity being the prerequisite for transfer & ADL, it is necessary to restore upright standing in stroke patients. The cognitive & goal-oriented approaches, Motor imagery (MI) and motor re-learning program (MRP) have been effective to enhance STS activity in stroke patients. However, the effect of MI with MRP for better outcome is not known. The current research aimed to evaluate the integrated result of MI & MRP on STS activity in stroke. Thirty-six acute ischemic stroke patients were enrolled. Patients received MI for 30 minutes/day followed by MRP for 45 minutes/day, five times/week for 3 weeks. The pre & post intervention was assessed with outcome measures like Fugl-Myer Assessment-Lower Extremity (FMA-LE), Motor Assessment Scale (MAS), Kinesthetic & Visual Imagery Questionnaire (KVIQ) and 5-times sit-to-stand (5-times STS). The results showed reduction in sensory & motor impairment (FMA-LE: t-value=397.00), improvement in motor function (MAS: t-value=289.00), better clarity in sensation & image (KVIQ: t-value= 137.358 & 132.355 respectively) & ability to perform STS activity improved (5-times STS: t-value=107.00) with P=<0.001.The combined approach of MI & MRP designed to improve STS activity in stroke patients was viable in the study. This clinically innovative strategy is effective approach in improving motor functions affecting transfer activities & ADL.